Southern Illinois Salukis vs South Dakota Coyotes Predictions October 10, 2026
South Dakota will beat Southern Illinois 31-24 in our October 10 forecast, with the Coyotes’ productive passing and rushing performances providing the strongest matchup reason. Southern Illinois brings enough passing production to threaten a close finish, while South Dakota’s latest rout leaned heavily on takeaways. Neither South Dakota -10.5 (+115) nor the 58.5 total offers a strong enough edge for an actionable wager.
Southern Illinois Salukis vs South Dakota Coyotes prediction and best bet
South Dakota is the pick to win, but the official betting recommendation is Pass. The Coyotes’ latest offensive performance gives them a reasonable path to controlling this matchup without needing another extraordinary turnover haul. Asking them to cover a double-digit spread is a separate, more demanding proposition.
Southern Illinois’ passing production makes the underdog competitive in this forecast. Its recent execution problems favor South Dakota, but treating those mistakes as inevitable would overstate the advantage. A seven-point projected margin reflects that tension: the Coyotes get the victory, while neither spread price earns a recommendation.
Odds, game time and how to watch
Game: Southern Illinois Salukis at South Dakota Coyotes, Saturday, October 10, 2026. This is a 2026 college football matchup.
Venue: The DakotaDome in Vermillion, South Dakota.
Records and rankings: South Dakota is 4-2 overall and Southern Illinois is 3-3. Both are 1-1 in Missouri Valley Football Conference play. Southern Illinois’ October 5 update identified the Coyotes as No. 10 and the Salukis as No. 25.