Get NFL picks, expert predictions, odds and scores for September 27, 2026. Open any matchup for current lines, consensus picks and SportsJaw game analysis.
| Date & time | Matchup | Spread | Moneyline | Total | Predictions |
|---|---|---|---|---|---|
New York Jets0Detroit Lions0 | +7 (-113)-7 (-107) | +260-325 | O 50 (-110)U 50 (-110) | Predictions: New York Jets vs Detroit Lions prediction | |
Houston Texans0Indianapolis Colts0 | -1.5 (-110)+1.5 (-110) | -123+103 | O 42.5 (-108)U 42.5 (-110) | Predictions: Houston Texans vs Indianapolis Colts prediction | |
New England Patriots0Jacksonville Jaguars0 | +3 (-110)-3 (-108) | +135-155 | O 46.5 (-115)U 46.5 (-105) | Predictions: New England Patriots vs Jacksonville Jaguars prediction | |
Carolina Panthers0Cleveland Browns0 | -2 (-110)+2 (-110) | -130+110 | O 41.5 (-110)U 41.5 (-110) | Predictions: Carolina Panthers vs Cleveland Browns prediction | |
Los Angeles Chargers0Buffalo Bills0 | +7 (-110)-7 (-110) | +274-340 | O 50.5 (-110)U 50.5 (-110) | Predictions: Los Angeles Chargers vs Buffalo Bills prediction | |
Kansas City Chiefs6Miami Dolphins0 | -10 (-105)+10 (-115) | -620+458 | O 45 (-110)U 45 (-110) | Predictions: Kansas City Chiefs vs Miami Dolphins prediction | |
Cincinnati Bengals0Pittsburgh Steelers0 | -3 (-112)+3 (-108) | -165+140 | O 42.5 (-108)U 42.5 (-113) | Predictions: Cincinnati Bengals vs Pittsburgh Steelers prediction | |
Tennessee Titans0New York Giants0 | +2.5 (-110)-2.5 (-110) | +115-135 | O 37.5 (-110)U 37.5 (-110) | Predictions: Tennessee Titans vs New York Giants prediction | |
Seattle Seahawks0Washington Commanders0 | -8.5 (-105)+8.5 (-115) | -400+315 | O 40.5 (-105)U 40.5 (-115) | Predictions: Seattle Seahawks vs Washington Commanders prediction | |
Arizona CardinalsSan Francisco 49ers | +7.5 (-110)-7.5 (-110) | +303-380 | O 48.5 (-108)U 48.5 (-110) | View picks: Arizona Cardinals vs San Francisco 49ers prediction | |
Minnesota VikingsTampa Bay Buccaneers | -1 (-110)+1 (-110) | -116-104 | O 42.5 (-110)U 42.5 (-108) | View picks: Minnesota Vikings vs Tampa Bay Buccaneers prediction | |
Las Vegas RaidersNew Orleans Saints | +3.5 (-115)-3.5 (-105) | +155-180 | O 43.5 (-115)U 43.5 (-105) | View picks: Las Vegas Raiders vs New Orleans Saints prediction | |
Baltimore RavensDallas Cowboys | -3.5 (-105)+3.5 (-115) | -175+150 | O 53.5 (-110)U 53.5 (-110) | View picks: Baltimore Ravens vs Dallas Cowboys prediction | |
Los Angeles RamsDenver Broncos | -1.5 (-110)+1.5 (-108) | -126+108 | O 44 (-110)U 44 (-110) | View picks: Los Angeles Rams vs Denver Broncos prediction |
