New England Patriots vs Jacksonville Jaguars prediction: Jaguars 24, Patriots 22
Jacksonville will beat New England, Jaguars 24, Patriots 22, with Parker Washington’s receiving production and the Patriots’ defensive absences providing the strongest matchup reason. The edge is slight: New England’s early run defense and Jacksonville’s uneven performances keep confidence low. Neither the supplied three-point spread nor the total of 46 offers a compelling wager, so the official recommendation is Pass.
New England Patriots vs Jacksonville Jaguars prediction and best bet
Jacksonville gets the pick in a close game because Washington gives its passing attack a productive option against a defense missing Dre'Mont Jones and Quintayvious Hutchins. Trevor Lawrence’s four-touchdown opener shows what the Jaguars can produce, although his more modest outing at Denver keeps that performance from carrying the forecast by itself.
New England has a credible route to the win, too. Its defense held each of its first two opponents below 100 rushing yards, and Drake Maye generated several long completions against Pittsburgh. Those strengths make taking Jacksonville -3 (-105) uncomfortable. They also fall short of making Patriots +3 (-115) a compelling purchase. Best bet: Pass.
Odds, game time and how to watch
Game: New England Patriots at Jacksonville Jaguars, Week 3 of the 2026 NFL season.
Kickoff: Sunday, September 27, 2026, at 1 p.m. EDT.
Venue: EverBank Stadium, Jacksonville.
Watch: CBS/WBZ; Jacksonville’s listings include CBS47 and Paramount+.
Records: New England Patriots 1-1; Jacksonville Jaguars 1-1.
SportsJaw odds: New England Patriots +3 (-110); Jacksonville Jaguars -3 (-108). Moneyline: New England Patriots +135; Jacksonville Jaguars -155. Total: Over 46.5 (-115); Under 46.5 (-105).

