NFL Matchups
San Francisco 49ers vs Los Angeles Rams Prediction

Make Your Picks[ - ]

 
SF
LAR
Open
Side
-6.5
+6.5
+7
Moneyline
-300
+245
+280
Total
O 43.25
U 43.25
45.5

Make your predictions for San Francisco 49ers vs Los Angeles Rams to showcase your betting acumen and earn tips for your winners!

San Francisco 49ers vs
Los Angeles RamsPredictions & Preview

49ers Favored by 6.5 Points Over Rams in NFC West Showdown at SoFi Stadium

As we approach the weekend, NFL fans can look forward to an exciting match-up between the San Francisco 49ers and the Los Angeles Rams. The 49ers, currently at 1-1, are favored by oddsmakers as a 7-point favorite over the 0-2 Rams. The line has since shifted to San Francisco -6.5, indicating a slight adjustment in favor of the Rams. Stay tuned for our in-depth analysis and NFL picks for this NFC West showdown.

Betting Odds

  • Moneyline: 49ers -300 | Rams +245
  • Spread: 49ers -6.5 (-110) | Rams +6.5 (-110)
  • Total: Over/Under 43.5 (-110)
  • Based on the moneyline, the implied probability that San Francisco will win straight-up is 75%.

San Francisco vs Los Angeles Stats

49ers vs Rams prediction infographic
View stats & injuries for 49ers vs Rams

San Francisco 49ers

The San Francisco 49ers are coming off a successful 2023 season, making it to the Super Bowl, and have high expectations for this season. The team has started off well, with a strong road record last season and a convincing win against the Jets in week 1. However, they faced a tough challenge against the Vikings in their last game. Quarterback Brock Purdy has been performing well, completing over 72% of his passes. The team misses Christian McCaffery, but Jordan Mason has stepped up in his absence. The defense has been solid, allowing an average of 21 points per game so far. With a power ranking of 2, the 49ers are currently ranked 9 in offense and 16 in defense. They have a 1-0 record this season.

Los Angeles Rams Analysis

Despite high expectations following a playoff appearance and a 10-7 season, the Los Angeles Rams are facing challenges early in the season. After a close loss in the opener, they were soundly defeated by the Arizona Cardinals in week 2. Injuries to key players, including star wide receivers Puka Nacua and Cooper Kupp, have added to their woes. However, quarterback Matt Stafford has shown promise, completing 70% of his passes. The team's run game and defense need improvement, as they have struggled to score and have allowed an average of 33.5 points per game. The Rams currently have a power ranking of 11 and are ranked #28 for offense and #31 for defense. Despite a tough start, they will look to bounce back in their upcoming game against San Francisco.

49ers Expected to Dominate In-State Rival Rams by 7+ Points in Showdown at SoFi Stadium

I anticipate the San Francisco 49ers will secure a victory against their in-state rival, the Los Angeles Rams, by a margin of at least 7 points this Sunday afternoon. Despite a recent defeat, the 49ers have shown promise this season and have successfully navigated their various injuries, particularly in the run game where Jordan Mason has excelled in the absence of CMAC. Quarterback Brock Purdy has also been performing impressively to kick off the season. Known for their strong performance on the road, the 49ers tend to have an especially enthusiastic following in Los Angeles, often making it feel like a home game at SoFi Stadium. Conversely, the Rams are facing challenges with their season appearing to be in a precarious position following a recent loss to Arizona and injuries to both of their star receivers.

Sources: [ 1 ] [ 2 ] [ 3 ] [ 4 ] [ 5 ]

BEST
BETS
Guaranteed Picks
from NFL Experts

Best Bets From The Most Profitable NFL Handicappers

9/22/2024 at 1:00PM
Green Bay PackersGreen Bay
Tennessee TitansTennessee
9/22/2024 at 1:00PM
Philadelphia EaglesPHI
New Orleans SaintsNO
9/22/2024 at 1:00PM
Denver BroncosDenver
Tampa Bay BuccaneersTampa Bay
9/22/2024 at 1:00PM
Chicago BearsChicago
Indianapolis ColtsIND
9/22/2024 at 4:05PM
Miami DolphinsMiami
Seattle SeahawksSeattle
9/22/2024 at 4:25PM
Detroit LionsDetroit
Arizona CardinalsArizona
9/22/2024 at 8:20PM
Kansas City ChiefsKC
Atlanta FalconsAtlanta
Follow Expert Picks