Buffalo Bills versus Detroit Lions Head-to-head history

Scores, recaps and recorded betting results from the five most recent meetings in SportsJaw history.

SportsJaw’s stored game records date back to 2015. The news feed shows up to the five most recent completed meetings.

Head-to-head history

Last five meetings

Recent game recaps, recorded odds and betting results

Sept 17, 2026	Score	Moneyline	Spread	Game total
Detroit LionsDET	31	+200 L	+5.5 (-110) L	O 54.5 (-115) W U 54.5 (-105) L
Buffalo BillsBUF	41	-250 W	-5.5 (-110) W	O 54.5 (-115) W U 54.5 (-105) L

Buffalo Bills defeated Detroit Lions 41-31

Buffalo Bills defeated Detroit Lions 41-31 on September 17, 2026, a 10-point decision in the series. Buffalo Bills' strongest period was the 1st quarter, when it outscored its opponent 14-0. Against SportsJaw's recorded Detroit Lions +5.5 (-110) spread, Buffalo Bills covered, while the 72 combined points finished over the recorded total of 54.5.

Team	1	2	3	4	T
DET	0	10	7	14	31
BUF	14	13	7	7	41

Dec 15, 2024	Score	Moneyline	Spread	Game total
Buffalo BillsBUF	48	+115 W	+2.5 (-110) W	O 55.5 (-110) W U 55.5 (-110) L
Detroit LionsDET	42	-135 L	-2.5 (-110) L	O 55.5 (-110) W U 55.5 (-110) L

Buffalo Bills defeated Detroit Lions 48-42

Team	1	2	3	4	T
BUF	14	7	14	13	48
DET	0	14	7	21	42

Nov 24, 2022	Score	Moneyline	Spread	Game total
Buffalo BillsBUF	28	-435 W	-9.5 (-110) L	O 54.5 (-110) L U 54.5 (-110) W
Detroit LionsDET	25	+350 L	+9.5 (-110) W	O 54.5 (-110) L U 54.5 (-110) W

Buffalo Bills defeated Detroit Lions 28-25

Team	1	2	3	4	T
BUF	7	10	2	9	28
DET	7	7	0	11	25

Aug 13, 2021	Score	Moneyline	Spread	Game total
Buffalo BillsBUF	16	+120 W	+2 (-110) W	O 36.5 (-110) L U 36.5 (-110) W
Detroit LionsDET	15	-140 L	-2 (-110) L	O 36.5 (-110) L U 36.5 (-110) W

Aug 23, 2019	Score	Moneyline	Spread	Game total
Buffalo BillsBUF	24	— —	-3.5 (-110) W	O 41 (-110) W U 41 (-110) L
Detroit LionsDET	20	— —	+3.5 (-110) L	O 41 (-110) W U 41 (-110) L

Verified performance

Experts who know these teams

Weighted grade based on 75% profit from head-to-head bets and 25% from profits earned betting on either team.

CovergirlWeighted grade50+$1,491 · 4 picks3–1 W–L · 75.0%2

TweiskoffWeighted grade44+$1,818 · 3 picks3–0 W–L · 100.0%3

DemarcusBryantWeighted grade44+$1,718 · 3 picks2–1 W–L · 66.7%

RankHandicapperGradeProfit

Expert grades weight verified head-to-head profit at 75% and profit on other games involving either team at 25%, with a confidence adjustment until ten qualifying picks are recorded.