Arizona Cardinals vs
San Francisco 49ersPredictions & Preview

San Francisco 49ers Favored by 7.5 Points in NFC West Showdown Against Arizona Cardinals

On October 6, 2024, at 3:05 PM ET, the Arizona Cardinals (1-3) will face the San Francisco 49ers (2-2) at Levi's Stadium in Santa Clara, CA, broadcasted on Fox. The 49ers are favored by 7.5 points, with an over/under of 49.5 points. The Cardinals seek to recover from a recent loss, while the 49ers are riding high from a victory and aim to continue their success. This NFC West matchup is set to be an intense battle as both teams vie for a crucial win. for more information, check NFL Betting Picks.

Betting Odds

• Moneyline: Cardinals +285 | 49ers -355
• Spread: Cardinals +7.5 (-110) | 49ers -7.5 (-110)
• Total: Over/Under 50 (-110)
• Based on the moneyline, the implied probability that San Francisco will win straight-up is 78%.

Arizona vs San Francisco Stats

Arizona Cardinals

On September 30, 2024, the Arizona Cardinals faced a tough 42-14 loss to the Washington Commanders, with a critical pass interference call against cornerback Sean Murphy-Bunting shifting the momentum in favor of the Commanders. Despite a touchdown connection between quarterback Kyler Murray and rookie Marvin Harrison Jr., the Cardinals struggled offensively, particularly without tight end Trey McBride who was out with a concussion. Running back James Conner showed promise, but adjustments are crucial moving forward, especially on defense as they prepare to face the San Francisco 49ers. Defensive coordinator Nick Rallis emphasizes the need to address internal issues to improve their performance, particularly against the run. Quarterback Kyler Murray acknowledges the importance of his mobility in the game, as the team deals with injuries to key players such as kicker Matt Prater and right tackle Kelvin Beachum. Currently ranked 21st in power rankings, the Cardinals are 4th in offense, averaging 27.33 points per game, and 19th in defense, allowing an average of 21.33 points against them per game, with a 1-3 record for the season.

San Francisco 49ers Analysis

The San Francisco 49ers bounced back from a two-game skid with a dominating 30-13 win over the New England Patriots, thanks to standout performances from quarterback Brock Purdy, linebacker Fred Warner, and running back Jordan Mason. The defense delivered six sacks and a touchdown, while Purdy showcased his skills with deep passes and Mason rushed for 123 yards. The victory was a much-needed confidence boost for the team, who now sit second in the NFC West behind the Seattle Seahawks. Despite injury concerns, the 49ers are optimistic about their upcoming matchups against divisional rivals, emphasizing the importance of depth on the D-line.With a power ranking of 3 and ranking 8th for offense, the 49ers are gearing up for a critical stretch of games, including facing the Seahawks on "Thursday Night Football."

San Francisco 49ers Showcased Dominance and Superiority Ahead of Cardinals Matchup

The San Francisco 49ers have demonstrated exceptional strength this season, showcasing an average of 25.8 points per game coupled with a defense that limits opponents to just 20.5 points. Their impressive offensive output ranks them second in the NFL, averaging 413 total yards per game, while their defense holds opponents to 295.3 yards, placing them ninth in the league. With an average of 6.3 yards per play, the 49ers rank third in the NFL and lead in total offensive efficiency at 57.71%. These outstanding statistics underscore the 49ers' dominance and set them up for success in their upcoming matchup against the Cardinals. In contrast, the struggling Cardinals are averaging just 24 points per game and rank 29th in defense, presenting a clear mismatch. Betting on the 49ers to cover the spread in this game is a wise choice given their consistent performance and overall superiority.

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