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  1. Home
  2. NCAAF Picks
  3. Houston Cougars vs Colorado Buffaloes
Fri 10:15 PM ET
Houston Cougars logo
Houston
Cougars
6-2
versus
Colorado Buffaloes logo
Colorado
Buffaloes
3-6
NCAAF · Houston Cougars at Colorado Buffaloes

Your Picks on Houston vs Colorado

Picks close 15 minutes before game time (ET)
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Moneyline
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Houston vs Colorado consensus picks

Houston Cougars72%
28%Colorado Buffaloes
Odds comparison

Sportsbook lines for this game

Current lines

MatchupBest availableDraftKingsFanDuelBetMGMCaesarsCircaBet105BetOnlineBovadaHard RockHeritageIntertopsLowvigPinnacleSportsbettingUnibetYouWagertheScore Bet
Nov 13, 10:15 PM ETHouston CougarsColorado Buffaloes
Best available-340Circa+310Unibet
DraftKings-360+285
FanDuel-385+310BEST
BetMGM-350+290
Caesars——
Circa-340BEST+280
Bet105-345+284
BetOnline——
Bovada-350+275
Hard Rock-425+300
Heritage-371+293
Intertops——
Lowvig——
Pinnacle-342+281
Sportsbetting——
Unibet-420+310BEST
YouWager-350+270
theScore Bet-380+290

Houston Cougars vs Colorado Buffaloes Prediction, Odds and Best Bet

Game time: November 13, 2026 at 10:15 PM ET

Venue: Folsom Field — Boulder, CO

Article updated Nov 12, 8:56 AM EST

By SportsJaw Editorial Team

Houston will beat Colorado, with a projected score of Houston 34, Colorado 20. The Cougars’ stronger rushing production and better quarterback touchdown-to-interception profile give them the clearest matchup advantages. Houston -9.5 (-112) is the strongest wager at the supplied price, with medium confidence in the forecast. The total of 51.5 is a pass despite a projection that leans over.

Houston Cougars vs Colorado Buffaloes prediction and best bet

Houston -9.5 (-112) is the best bet for this Nov. 13 college football matchup. The case starts with production verified in Houston’s official preview: the Cougars have the stronger rushing output, while their quarterbacks have thrown nine more touchdown passes and eight fewer interceptions than Colorado’s.

Those advantages favor Houston sustaining drives and avoiding costly mistakes. They also offer a reasonable route to a double-digit win, although a road favorite must do more than simply outperform its opponent to cover this spread.

Other analysts also favor Houston. College Football Charts projects Houston 37, Colorado 20, while Colorado Buffaloes on SI predicts Houston 31, Colorado 20. Their agreement is useful context, but the six-point difference in their projected margins matters when judging the spread.

Odds, game time and how to watch

Game time: Friday, Nov. 13, 2026, at 8:15 p.m. Mountain time, according to Colorado’s official gameday announcement.

Venue: Folsom Field, Colorado’s home stadium.

Records and standings: No. 14 Houston is 7-2 overall and 4-2 in the Big 12. Colorado is 3-6 overall and 1-5 in conference play. CBS reports Houston was one of five teams tied for third in the conference after beating Cincinnati.

21+. Gambling problem? Call 1-800-GAMBLER. Picks are opinions, not guarantees. Past results do not predict future outcomes.

SportsJaw spread and moneyline: Houston -9.5 (-112) and -366 to win outright; Colorado +9.5 (-105) and +299 to win outright.

SportsJaw total: Over 51.5 (-105) or Under 51.5 (-108).

Houston Cougars outlook

Houston averages 203.5 rushing yards per game and has scored 16 rushing touchdowns. That gives the Cougars a productive foundation without requiring every possession to depend on a successful pass. Establishing the run would also make it harder for Colorado to concentrate on defending one part of the offense.

The quarterback comparison strengthens Houston’s outlook. Its advantage in touchdown passes and interceptions suggests the Cougars have combined scoring production with better ball security. That is particularly useful when laying points, because an otherwise productive offense can lose its covering margin through a small number of mistakes.

Defensively, Houston has allowed 21.3 points per game and collected 13 takeaways through nine games, comprising eight interceptions and five fumble recoveries. CBS reports the Cougars most recently beat Cincinnati 31-24 at home. That seven-point result is a reminder that picking Houston to win and backing Houston to cover are separate judgments.

Colorado Buffaloes outlook

Colorado has a meaningful receiving threat in Joseph Williams, whose 853 receiving yards and six touchdowns offer a route to keeping pace. Quarterbacks Julian Lewis and Isaac Wilson have combined for 2,145 passing yards and 14 touchdowns, so the Buffaloes have passing production to build around.

Their combined 10 interceptions are the concern against a defense that has already generated takeaways. Colorado’s route to an upset becomes more credible if its quarterbacks can find Williams while avoiding possessions that give Houston an easy scoring opportunity.

The Buffaloes average 140 rushing yards per game and have nine rushing touchdowns. Jaquail Smith has contributed 396 rushing yards and one touchdown. Colorado does not have to match Houston’s rushing average to compete, but enough early-down success would help keep its offense from relying too heavily on the passing game.

Key matchup factors

The central question is whether Houston’s stronger offensive production translates into control of this particular game. Its rushing advantage creates a plausible path, but offensive averages alone do not measure how effectively Colorado will defend the run on Friday.

The outside analysts emphasize different elements. College Football Charts bases its Houston pick on a favorable passing-efficiency matchup and assigns the Cougars an 81% win probability. SI emphasizes Colorado’s need to limit Houston’s rushing success and create impact plays through the air. The 81% figure belongs to that analyst’s projection; it is not SportsJaw’s confidence rating.

As of Nov. 12 at 13:52 UTC, the blended consensus favors Houston -9.5 (-112) at 74%, up one percentage point from the previous day. Its estimated combined sample is 444 Houston selections and 156 Colorado selections out of 600. These are modeled equivalents, not observed sportsbook tickets or a count of SportsJaw member picks.

Houston Cougars vs Colorado Buffaloes spread prediction

The spread recommendation is Houston -9.5 (-112). A projected 14-point victory leaves 4.5 points above the required margin, with the rushing and quarterback comparisons supplying the football rationale. This is an ordinary edge rather than an overwhelming one.

Colorado +9.5 (-105) remains a credible opposing case if Williams helps the Buffaloes sustain scoring drives and their quarterbacks protect the ball. SI’s 11-point Houston projection would clear the spread by only 1.5 points. That narrow cushion limits confidence even though both outside forecasts favor a Houston cover.

Houston Cougars vs Colorado Buffaloes total prediction

Pass on Over 51.5 (-105) and Under 51.5 (-108). The projected score totals 54 points, but that modest lean above the line is less persuasive than the side. Houston’s rushing production could support scoring drives or help it manage a lead, producing different outcomes for the total.

The analysts’ forecasts also straddle the number: SI projects 51 combined points, while College Football Charts projects 57. The blended consensus favors Over at 62%, although the previous-day change moved two percentage points toward Under. Those preferences describe sentiment, not a demonstrated total-betting edge.

Houston Cougars vs Colorado Buffaloes Projected Score & Betting Picks

Game forecast: Houston 34, Colorado 20, with medium confidence. Houston’s rushing production, quarterback ball security and defensive takeaway record support the selection. Colorado’s strongest counterargument is a productive passing performance centered on Williams that keeps the game close.

The official SportsJaw wager is Houston -9.5 (-112). The total remains a pass. The projected score is an editorial judgment about the matchup, with enough uncertainty around Colorado’s scoring contribution to keep the total off the betting card.

SportsJawGame Predictions
Predicted score

Cougars34

Buffaloes20

Projected winner Houston CougarsConfidencemedium
Pick on the Spread

Published pick: Spread: Houston Cougars -9.5 (-112)

Pick on the Total

Published pick: Pass on Over 51.5 (-105) and Under 51.5 (-108)

Sources

  • University of Houston AthleticsPREVIEW: #14 Houston Faces Colorado on Friday Night
  • University of Colorado AthleticsColorado vs. Houston: Know Before You Go
  • CBS SportsNo. 14 Houston looks to stay in CFP hunt at Colorado
#HoustonCougars#ColoradoBuffaloes

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Written by

SportsJaw Editorial Team

SportsJaw's editorial organization researches matchup data, current odds, injuries and reporting, then validates each published preview against its listed sources and displayed markets.

About our editorial process

SportsJaw Cougars vs Buffaloes game preview analysis and predictions incorporate current odds, injury reports, team statistics and market data. Information is updated regularly, but lines and player availability can change. Please confirm current information before wagering. View history of past Cougars vs Buffaloes matchups or learn how our predictions work.

Current matchup data

Lines, trends and availability

Line movement since open

  • Moneyline · Houston Cougars-426 → -360Moved
  • Moneyline · Colorado Buffaloes+308 → +290Moved
  • Spread · Houston Cougars-10.5 (-150) → -9.5 (-108)Moved
  • Spread · Colorado Buffaloes+10.5 (-100) → +9.5 (-112)Moved
  • Total · Over47.5 (-110) → 51.5 (-102)Moved
  • Total · Under47.5 (-110) → 51.5 (-111)Moved

ATS and O/U trends

Houston Cougars
6-2 matchup record · 4-6-0 ATS · 5-5-0 O/U
Last 10 completed games on file
Colorado Buffaloes
3-6 matchup record · 3-6-1 ATS · 4-5-1 O/U
Last 10 completed games on file

Injuries and availability

From the published research (2026-11-12T04:35:20.672Z). Availability may have changed; review the cited sources.

No verified injury or availability note was included in the published matchup research.

Recent head-to-head

  • 2025-09-12Colorado Buffaloes 20 · Houston Cougars 36
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