| Score | Moneyline | Spread | Game total | |
|---|---|---|---|---|
| Colorado BuffaloesCOLO | 20 | +160 L | +4 (-110) L | O 45.5 (-110) W U 45.5 (-110) L |
| Houston CougarsHOUSTO | 36 | -191 W | -4 (-110) W |
Houston Cougars defeated Colorado Buffaloes 36-20
Houston Cougars defeated Colorado Buffaloes 36-20 on September 12, 2025, a 16-point decision in the series. Houston Cougars' strongest period was the 1st quarter, when it outscored its opponent 10-0. Against SportsJaw's recorded Colorado Buffaloes +4 (-110) spread, Houston Cougars covered, while the 56 combined points finished over the recorded total of 45.5.
| Team | 1 | 2 | 3 | 4 | T |
|---|---|---|---|---|---|
| Colorado Buffaloes | 0 | 14 | 0 | 6 | 20 |
| Houston Cougars | 10 | 6 | 10 | 10 | 36 |

