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NHL PicksThu 7:00 PM ET
Florida Panthers logo
Florida
Panthers
5-2
versus
Pittsburgh Penguins logo
Pittsburgh
Penguins
3-6
NHL · Florida Panthers at Pittsburgh Penguins

Your Picks on Panthers vs Penguins

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Florida vs Pittsburgh consensus picks

Florida Panthers56%
44%Pittsburgh Penguins
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Florida Panthers vs Pittsburgh Penguins Predictions Today

Game time: October 22, 2026 at 7:00 PM ET

Venue: PPG Paints Arena — Pittsburgh, PA

Article updated Oct 22, 12:09 AM EDT

By SportsJaw Editorial Team

Pittsburgh is projected to beat Florida, Penguins 4, Panthers 3, with Florida’s road back-to-back and Jacob Markstrom’s injury providing the strongest matchup reason. Brady Tkachuk’s scoring surge makes the Panthers a dangerous opponent, keeping confidence low. Pittsburgh’s -112 moneyline does not offer a demonstrated betting edge, and neither the puck line nor total warrants an official wager. SportsJaw’s best bet is Pass.

Florida Panthers vs Pittsburgh Penguins prediction and best bet

Pittsburgh is the pick in a close game. Florida faces its second road game in two nights after losing 5-1 at Ottawa, and Markstrom’s absence adds uncertainty in goal. Those circumstances give the Penguins a slight edge in this October 22 NHL matchup.

The distinction is between picking a winner and paying for that outcome. Pittsburgh is favored at -120, but the case rests heavily on Florida’s difficulties rather than a proven Penguins advantage. The official SportsJaw wager is Pass, with both the puck line and total evaluated separately below.

Odds, game time and how to watch

Game: Florida Panthers at Pittsburgh Penguins, 2026-27 NHL season.

Time: Thursday, October 22, 2026, at 7 p.m. ET.

Venue: PPG Paints Arena.

Florida record: 5-3-2 after an October 21 loss at Ottawa ended a three-game winning streak.

SportsJaw moneyline: Florida +100; Pittsburgh -120.

SportsJaw puck line: Florida +1.5 (-235); Pittsburgh -1.5 (+210). Total: Over 6.5 (-133); Under 6.5 (+117).

Florida Panthers outlook

Florida’s best offensive argument is Brady Tkachuk. He scored in the Ottawa loss, and the Panthers’ recap credited him with seven goals over his previous four games. That finishing streak gives Florida a credible route to an outright win even after Wednesday’s setback.

21+. Gambling problem? Call 1-800-GAMBLER. Picks are opinions, not guarantees. Past results do not predict future outcomes.

Markstrom will miss one to two weeks with an upper-body injury sustained in practice. He had a 3-1-1 record, a 2.21 goals-against average and a .897 save percentage through six appearances. His absence changes Florida’s options, although it does not automatically mean his replacement will struggle.

Coach Paul Maurice said recalled goaltender Cooper Black will get playing time during Markstrom’s absence. Akira Schmid stopped 10 of 11 shots in the opening period against Ottawa. Neither detail confirms Thursday’s starter. On defense, Radko Gudas returned from a lower-body injury and played 17:03 after missing three games.

Pittsburgh Penguins outlook

Pittsburgh’s opportunity is to make Florida’s short turnaround matter. Forcing the Panthers to spend long stretches defending would be a useful route to victory, but that is a tactical possibility, not a claim about how the Penguins have performed this season.

The -120 moneyline makes Pittsburgh a modest favorite. The supplied reporting offers no current Penguins personnel or performance detail strong enough to turn that price into a confident recommendation. The home side gets the forecast edge because of the opponent’s circumstances, with Tkachuk’s form the clearest threat to that call.

Key matchup factors

The central question is how much weight to give Florida’s immediate setback. A five-goal concession is relevant to this turnaround, but one result should not erase the three consecutive wins that preceded it. Expecting another heavy defeat would be a stronger conclusion than the evidence warrants.

SportsJaw’s combined moneyline consensus favors Pittsburgh at 59%, with 354 selections against Florida’s 246 in a 600-selection equivalent sample, updated October 22 at 03:54 UTC. Those counts incorporate modeled sportsbook selections; they are not observed ticket totals, a standalone member poll or a 59% win probability.

The puck line and total are each split 50-50. Their listed leaders therefore carry no majority backing. The moneyline consensus supports the direction of the forecast, but it adds no independent evidence about either team’s on-ice quality.

Florida Panthers vs Pittsburgh Penguins spread prediction

Spread recommendation: Pass Florida Panthers +1.5 (-235) and Pittsburgh Penguins -1.5 (+210). The projected one-goal Pittsburgh win would leave Florida covering, but the Panthers’ cushion comes at a substantial price.

Pittsburgh -1.5 pays +210 but requires a victory by at least two goals. The forecast anticipates a closer contest, and Florida’s recent scoring threat argues against assuming separation. Neither the expensive underdog cushion nor the favorite’s larger payout supplies a convincing wager.

Florida Panthers vs Pittsburgh Penguins total prediction

Total recommendation: Pass Over 6.5 (-133) and Under 6.5 (+117). A 4-3 projection lands above the total, with Tkachuk’s scoring and Florida’s changing goaltending options making a seven-goal game plausible.

That projection is not enough to justify Over -133. Florida’s injury creates uncertainty rather than a guaranteed increase in goals, and there is no supported Pittsburgh scoring profile here to strengthen the Over. Under +117 offers a plus-money return, but price alone is no reason to oppose the forecast.

Florida Panthers vs Pittsburgh Penguins projected score

Game forecast: Pittsburgh Penguins 4, Florida Panthers 3. The short turnaround and Markstrom’s absence tip a narrow decision toward Pittsburgh. Florida’s recent winning streak and Tkachuk’s scoring surge are the strongest counterarguments.

Confidence is low. Pittsburgh is the projected winner, while the anticipated margin favors Florida’s puck line and the projected goals lean Over. Neither market offers demonstrated value at its supplied price, so the single official SportsJaw wager remains Pass.

SportsJawGame Predictions
Predicted score

Panthers3

Penguins4

Projected winner Pittsburgh PenguinsConfidencelow
Pick on the Spread

Published pick: Pass Florida Panthers +1.5 (-235) and Pittsburgh Penguins -1.5 (+210).

Pick on the Total

Published pick: Pass Over 6.5 (-133) and Under 6.5 (+117).

Sources

  • Florida Panthers / NHL.comRECAP: Brady Tkachuk scores, but Panthers open road trip with loss to Senators
  • NHL.comNHL Status Report: Sanderson returns for Senators against Panthers

SportsJaw Panthers vs Penguins game preview analysis and predictions incorporate current odds, injury reports, team statistics and market data. Information is updated regularly, but lines and player availability can change. Please confirm current information before wagering. View history of past Panthers vs Penguins matchups or learn how our predictions work.

Current matchup data

Lines, trends and availability

Crowd vs qualified handicappers

Moneyline crowd
Florida Panthers -106 · 100%
Moneyline qualified handicappers
Insufficient qualified picks
Qualified handicappers need at least 20 graded picks and a 52.5% win rate. A market needs at least three current qualified picks. Selection share is not a win probability.

Line movement since open

  • Moneyline · Florida Panthers-100 → -106Moved
  • Moneyline · Pittsburgh Penguins-100 → -112Moved
  • Spread · Florida Panthers-1.5 (+203) → +1.5 (-247)Moved
  • Spread · Pittsburgh Penguins+1.5 (-285) → -1.5 (+207)Moved
  • Total · Over6.5 (-113) → 6.5 (-140)Moved
  • Total · Under6.5 (-104) → 6.5 (+120)Moved

ATS and O/U trends

Florida Panthers
5-2 matchup record · 3-7-0 ATS · 5-5-0 O/U
Last 10 completed games on file
Pittsburgh Penguins
3-6 matchup record · 5-5-0 ATS · 7-3-0 O/U
Last 10 completed games on file

Injuries and availability

From the published research (2026-10-22T04:09:38.087Z). Availability may have changed; review the cited sources.

Markstrom will miss one to two weeks with an upper-body injury sustained in practice. He had a 3-1-1 record, a 2.21 goals-against average and a .897 save percentage through six appearances. His absence changes Florida’s options, although it does not automatically mean his replacement will struggle.

Coach Paul Maurice said recalled goaltender Cooper Black will get playing time during Markstrom’s absence. Akira Schmid stopped 10 of 11 shots in the opening period against Ottawa. Neither detail confirms Thursday’s starter. On defense, Radko Gudas returned from a lower-body injury and played 17:03 after missing three games.

That projection is not enough to justify Over -133. Florida’s injury creates uncertainty rather than a guaranteed increase in goals, and there is no supported Pittsburgh scoring profile here to strengthen the Over. Under +117 offers a plus-money return, but price alone is no reason to oppose the forecast.

Recent head-to-head

  • 2026-04-04Florida Panthers 4 · Pittsburgh Penguins 9
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