Buffalo Bills versus San Francisco 49ers Head-to-head history

SportsJaw’s stored game records date back to 2015. The news feed shows up to the five most recent completed meetings.

Head-to-head history

Last five meetings

Recent game recaps, recorded odds and betting results

Dec 1, 2024	Score	Moneyline	Spread	Game total
San Francisco 49ersSF	10	+245 L	+6.5 (-110) L	O 45.5 (-110) L U 45.5 (-110) W
Buffalo BillsBUF	35	-290 W	-6.5 (-110) W

Buffalo Bills defeated San Francisco 49ers 35-10

Team	1	2	3	4	T
SF	3	0	7	0	10
BUF	7	14	7	7	35

Dec 7, 2020	Score	Moneyline	Spread	Game total
Buffalo BillsBUF	34	+105 W	+1.5 (-110) W	O 48 (-110) W U 48 (-110) L
San Francisco 49ersSF	24	-125 L	-1.5 (-110) L

Buffalo Bills defeated San Francisco 49ers 34-24

Verified performance

Experts who know these teams

Weighted grade based on 75% profit from head-to-head bets and 25% from profits earned betting on either team.

1DrfeelgoodWeighted grade32+$909 · 1 picks1–0 W–L · 100.0%2ThetotalerWeighted grade31+$909 · 1 picks1–0 W–L · 100.0%3BluedevilWeighted grade30+$909 · 1 picks1–0 W–L · 100.0%

RankHandicapperGradeProfit

4Averagejoe1–0 W–L · 100.0%29+$9095Fisher491–0 W–L · 100.0%26+$9096Roderick8061–0 W–L · 100.0%26+$909772dolphins1–0 W–L · 100.0%25+$9098Barry7131–0 W–L · 100.0%25+$9099Miamimike1–0 W–L · 100.0%24+$45510Jw1–1 W–L · 50.0%24+$40911Thinkmakegrow1–0 W–L · 100.0%22+$45512Kingjames1–0 W–L · 100.0%21+$45513Aliencreation1–0 W–L · 100.0%15+$17414Covers1–0 W–L · 100.0%15+$10015Billywaters1–1 W–L · 50.0%15-$9116Steved0–1 W–L · 0.0%14-$10017Tgodfrey0–0 W–L · —13$01817076629050–1 W–L · 0.0%13-$50019Jamescashiola1–0 W–L · 100.0%12+$9120Josh7200–0 W–L · —11$0

Expert grades weight verified head-to-head profit at 75% and profit on other games involving either team at 25%, with a confidence adjustment until ten qualifying picks are recorded.