Buffalo Bills Favored to Win Season Opener Against Arizona Cardinals at Highmark Stadium
In the opening weekend of NFL action, the Arizona Cardinals take on the Buffalo Bills at Highmark Stadium. The Cardinals, who had a disappointing 4-13 record in 2023, are
Game outlook
In the opening weekend of NFL action, the Arizona Cardinals take on the Buffalo Bills at Highmark Stadium. The Cardinals, who had a disappointing 4-13 record in 2023, are counting on the health of their quarterback to turn things around. Meanwhile, the Bills, who finished 11-6 last season, have some unanswered questions heading into the new year. Buffalo is favored to win by 6 points, with the current line at Buffalo -6.5. The game kicks off at 1:00 EST in Orchard Park, New York.
Betting Odds
Moneyline: Cardinals +248 | Bills -300
Spread: Cardinals +6.5 (-110) | Bills -6.5 (-110)
Total: Over/Under 47 (-110)
Based on the moneyline, the implied probability that Buffalo will win straight-up is 75%.
Arizona Cardinals
The Arizona Cardinals have struggled in recent seasons, with head coach Jonathan Gannon leading the team to back-to-back four-win seasons. Franchise QB Kyler Murray missed half the previous season due to injuries but is now healthy and has a new top target in first-round pick Marvin Harrison Jr. The addition of Harrison Jr. gives Murray a downfield threat, which could open up more opportunities for the QB. The team has also made significant upgrades on defense with acquisitions like DE Justin Jones and DT Bilal Nichols. Despite some injury concerns, the Cardinals are looking to improve on their offensive and defensive rankings from last season. Their current power ranking is 24, with them ranked 24 in offense, 31 in defense, and holding a record of 0-0 this season.