Arizona Cardinals versus Detroit Lions Head-to-head history

Scores, recaps and recorded betting results from the five most recent meetings in SportsJaw history.

SportsJaw’s stored game records date back to 2015. The news feed shows up to the five most recent completed meetings.

Head-to-head history

Last five meetings

Recent game recaps, recorded odds and betting results

Oct 11, 2026	Score	Moneyline	Spread	Game total
Detroit LionsDET	45	-240 W	-5.5 (+100) W	O 55 (-110) W U 55 (-110) L
Arizona CardinalsARI	21	+200 L	+5.5 (-110) L	O 55 (-110) W U 55 (-110) L

Detroit Lions defeated Arizona Cardinals 45-21

Detroit Lions defeated Arizona Cardinals 45-21 on October 11, 2026, a 24-point decision in the series. Detroit Lions' strongest period was the 2nd quarter, when it outscored its opponent 24-0. Against SportsJaw's recorded Detroit Lions -5.5 (+100) spread, Detroit Lions covered, while the 66 combined points finished over the recorded total of 55.

Team	1	2	3	4	T
Detroit Lions	0	24	14	7	45
Arizona Cardinals	7	0	7	7	21

Sept 22, 2024	Score	Moneyline	Spread	Game total
Detroit LionsDET	20	-151 W	-3 (-110) W	O 51.5 (-110) L U 51.5 (-110) W
Arizona CardinalsARI	13	+131 L	+3 (-110) L	O 51.5 (-110) L U 51.5 (-110) W

Detroit Lions defeated Arizona Cardinals 20-13

Team	1	2	3	4	T
Detroit Lions	7	13	0	0	20
Arizona Cardinals	7	3	0	3	13

Dec 19, 2021	Score	Moneyline	Spread	Game total
Arizona CardinalsARI	12	-700 L	-13 (-110) L	O 48 (-110) L U 48 (-110) W
Detroit LionsDET	30	+500 W	+13 (-110) W	O 48 (-110) L U 48 (-110) W

Detroit Lions defeated Arizona Cardinals 30-12

Team	1	2	3	4	T
Arizona Cardinals	0	0	6	6	12
Detroit Lions	3	14	7	6	30

Sept 27, 2020	Score	Moneyline	Spread	Game total
Detroit LionsDET	26	+192 W	+5 (-110) W	O 55 (-110) L U 55 (-110) W
Arizona CardinalsARI	23	-230 L	-5 (-110) L	O 55 (-110) L U 55 (-110) W

Sept 8, 2019	Score	Moneyline	Spread	Game total
Detroit LionsDET	27	-145 P	-3 (-110) L	O 45.5 (-110) W U 45.5 (-110) L
Arizona CardinalsARI	27	+125 P	+3 (-110) W	O 45.5 (-110) W U 45.5 (-110) L