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NFL picks›Jacksonville Jaguars vs San Francisco 49ers predictions

JacksonvilleJaguarsVSSan Francisco49ers

Upcoming odds, recent results, and verified experts who have performed best when these teams take the field.

Odds & predictions

Upcoming matchups

No upcoming game is scheduled.Recent results and the experts who know these teams are below.
Head-to-head history

Past matchups

4 final results in SportsJaw history

Sep 28, 2025
Jacksonville Jaguars26San Francisco 49ers21Final
Nov 12, 2023
San Francisco 49ers34Jacksonville Jaguars3Final
Nov 21, 2021
San Francisco 49ers30Jacksonville Jaguars10Final
Dec 24, 2017
Jacksonville Jaguars33San Francisco 49ers44Final
Verified performance

Experts who know these teams

Weighted grade based on 75% profit from head-to-head bets and 25% from profits earned betting on either team.

1VegaspatWeighted grade31+$909 · 1 picks2ThetotalerWeighted grade29+$500 · 1 picks3AveragejoeWeighted grade27+$909 · 1 picks
RankHandicapperGradeProfit
4Georgew27+$9095MauriceJones27+$5006

Expert grades weight verified head-to-head profit at 75% and profit on other games involving either team at 25%, with a confidence adjustment until ten qualifying picks are recorded.

Teddy718
25
+$909
7Rainman25+$250
8Toufff24+$588
9Emc24+$500
10Ua200424+$500