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  1. Home
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  3. Arizona Cardinals vs Seattle Seahawks
Sun 4:25 PM ET
Arizona Cardinals logo
Arizona
Cardinals
3-5
versus
Seattle Seahawks logo
Seattle
Seahawks
4-4
NFL · Arizona Cardinals at Seattle Seahawks

Your Picks on Cardinals vs Seahawks

Picks close 15 minutes before game time (ET)
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Arizona vs Seattle consensus picks

Arizona Cardinals56%
44%Seattle Seahawks
Odds comparison

Sportsbook lines for this game

Current lines

MatchupBest availableDraftKingsFanDuelBetMGMCaesarsCircaBet105BetOnlineBovadaHard RockHeritageIntertopsLowvigPinnacleSportsbettingUnibetYouWagertheScore Bet
Nov 8, 4:25 PM ETArizona CardinalsSeattle Seahawks
Best available+520FanDuel-650Sportsbetting
DraftKings+500-700
FanDuel+520BEST-720
BetMGM+500-650BEST
Caesars+475-675
Circa+490-650BEST
Bet105+489-700
BetOnline+476-650BEST
Bovada+500-700
Hard Rock+475-750
Heritage+481-671
Intertops+500-700
Lowvig+476-650BEST
Pinnacle+489-704
Sportsbetting+476-650BEST
Unibet+475-670
YouWager+500-650BEST
theScore Bet+500-800

Arizona Cardinals vs Seattle Seahawks prediction, odds and best bet for November 8

Game time: November 8, 2026 at 4:25 PM ET

Venue: Lumen Field — Seattle, WA

Article updated Nov 3, 11:57 PM EST

By SportsJaw Editorial Team

The Seattle Seahawks are projected to beat the Arizona Cardinals, Seattle 26, Arizona 15, on November 8. Arizona’s uncertain running-back availability is the strongest personnel reason to favor Seattle, alongside two outside forecasts backing the Seahawks. Neither Seattle -12 (-110) nor the total of 41.5 (-110) offers a convincing betting edge, making the official SportsJaw recommendation Pass.

Arizona Cardinals vs Seattle Seahawks prediction and best bet

Seattle is the winner pick, with medium confidence in the straight-up forecast. Arizona’s backfield injuries give the Seahawks a potential matchup advantage, although Seattle has unresolved personnel questions of its own. The projected 11-point margin leaves a narrow cushion for Arizona +12, too small to make that side an official wager.

The best betting decision is Pass. BetMGM and the Dimers forecast reported by OregonLive favor Seattle to win, but their agreement is an analytical signal, not proof of value. Picking the winner is a different task from backing a favorite that must win by more than 12 points.

Odds, game time and how to watch

Game: Arizona Cardinals at Seattle Seahawks, Sunday, November 8, 2026, in Week 9 of the NFL season.

Kickoff: 1:25 p.m. PT, or 4:25 p.m. ET, as listed by the Seahawks and DK Network.

Venue: Lumen Field.

Broadcast: FOX. Radio coverage is listed on Seattle Sports 710AM and KIRO Newsradio 97.3 FM.

SportsJaw odds: Arizona Cardinals +12.5 (-110); Seattle Seahawks -12.5 (-110). Moneyline: Arizona Cardinals +500; Seattle Seahawks -650. Total: Over 41.5 (-110); Under 41.5 (-110).

21+. Gambling problem? Call 1-800-GAMBLER. Picks are opinions, not guarantees. Past results do not predict future outcomes.

Arizona Cardinals outlook

Arizona’s running-back availability is the clearest concern. DK Network’s November 3 injury update lists Jeremiyah Love as TBD with an ankle injury. He was ruled out at halftime in Week 8 after returning from a two-game absence. Bam Knight is also listed as TBD and is in concussion protocol.

Those statuses leave Arizona’s options uncertain rather than confirming either player will miss the game. If both are limited or unavailable, maintaining offensive balance could become harder. That possibility favors Seattle in the forecast, but treating Arizona’s rushing attack as already depleted would overstate what the injury update says.

For Arizona to outperform this projection, healthier backfield options would help. The Cardinals also have room to lose and still cover +12, so their straight-up outlook should not be confused with their chances against the spread.

Seattle Seahawks outlook

Seattle has availability questions across several positions. DK Network lists receiver Rashid Shaheed, offensive tackle Charles Cross, defensive tackle Leonard Williams and linebacker Uchenna Nwosu as TBD. None of those designations confirms an absence, but together they temper confidence in a comfortable Seattle victory.

The outside forecasts favor the Seahawks. BetMGM assigns Seattle 74.7% win confidence in its model, while OregonLive reports an 81.5% Seattle win probability from Dimers and a Seattle 26, Arizona 15 projection. Those figures belong to the respective models; they are not SportsJaw’s win probability or confidence rating.

The difference between those estimates matters. Both favor Seattle, yet they express different levels of certainty. Neither percentage measures the likelihood of Seattle covering the supplied 12-point spread.

Key matchup factors

Availability cuts both ways. Arizona’s running-back questions offer a reason to favor Seattle, while Seattle’s own injury list is the strongest personnel counterweight. The forecast assumes neither a fully healthy Cardinals backfield nor confirmed absences for the Seahawks.

At the November 4, 04:44 UTC consensus update, Arizona +12 (-110) led the blended spread view at 56%. Its modeled equivalent count was 336 selections to Seattle’s 264. Arizona’s share was up two percentage points from the November 2 snapshot.

Over 41.5 (-110) led the blended total view at 64%, equivalent to 384 modeled selections against 216 for Under. These are estimated consensus counts incorporating external sentiment and SportsJaw participation, not observed betting tickets. They describe preference, not win probability, and no separate member-only leader or qualified-handicapper pick is supplied.

Arizona Cardinals vs Seattle Seahawks spread prediction

Pass on Arizona Cardinals +12 (-110) and Seattle Seahawks -12 (-110). Our 11-point projected margin falls just inside Arizona’s number, but a one-point difference is a fragile basis for a wager when both teams have unresolved injuries.

BetMGM’s model favors Seattle to cover with 53.7% confidence, while the blended consensus favors Arizona. The supplied BetMGM summary does not identify the spread attached to that percentage, so it should not be treated as a measured edge at Seattle -12. The opposing views reinforce the distinction between a Seattle winner pick and a reliable spread selection.

Arizona Cardinals vs Seattle Seahawks total prediction

Pass on Over 41.5 (-110) and Under 41.5 (-110). The projected score totals 41, only half a point below the supplied number. That small separation is insufficient for an official Under recommendation.

OregonLive’s stated best bet is Under 44.5, a materially different threshold. Its analysis cites Seattle’s third-down, protection and red-zone difficulties and Arizona’s running-back concerns. Those are OregonLive’s reasons for its pick, rather than independently verified performance findings here. An Under recommendation at 44.5 should not automatically carry over to 41.5.

The 64% blended preference for Over points in the opposite direction. Neither that popularity nor the outside Under opinion gives SportsJaw a persuasive wager at the supplied total.

Arizona Cardinals vs Seattle Seahawks Projected Score & Betting Picks

Game forecast: Seattle Seahawks 26, Arizona Cardinals 15. Arizona’s backfield uncertainty and the two outside winner forecasts support Seattle, while the Seahawks’ own unresolved injuries are the strongest counterargument. Medium confidence fits the winner selection; it does not imply similar confidence in either betting market.

The projection is an editorial judgment, not a promised result. Pass on both supplied spread sides and both directions at 41.5. The single official SportsJaw betting recommendation is Pass.

SportsJawGame Predictions
Predicted score

Cardinals15

Seahawks26

Projected winner Seattle SeahawksConfidencemedium
Pick on the Spread

Published pick: Pass (article line changed)

Pick on the Total

Published pick: Pass on Over 41.5 (-110) and Under 41.5 (-110)

Sources

  • Seattle SeahawksHow To Watch, Listen And Follow Seahawks vs. Cardinals In Week 9 On Sunday, November 8
  • DK NetworkNFL Injury Report for Week 9: Latest Player Updates
  • BetMGM BettingCardinals vs Seahawks Prediction, Odds & Best Prop Bets – NFL, Week 9
#ArizonaCardinals#SeattleSeahawks

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Written by

SportsJaw Editorial Team

SportsJaw's editorial organization researches matchup data, current odds, injuries and reporting, then validates each published preview against its listed sources and displayed markets.

About our editorial process

SportsJaw Cardinals vs Seahawks game preview analysis and predictions incorporate current odds, injury reports, team statistics and market data. Information is updated regularly, but lines and player availability can change. Please confirm current information before wagering. View history of past Cardinals vs Seahawks matchups or learn how our predictions work.

Current matchup data

Lines, trends and availability

Line movement since open

  • Moneyline · Arizona Cardinals+550 → +500Moved
  • Moneyline · Seattle Seahawks-800 → -650Moved
  • Spread · Arizona Cardinals+13.5 (-110) → +12.5 (-110)Moved
  • Spread · Seattle Seahawks-13.5 (-110) → -12.5 (-110)Moved
  • Total · Over45.5 (-110) → 41.5 (-110)Moved
  • Total · Under45.5 (-110) → 41.5 (-110)Moved

ATS and O/U trends

Arizona Cardinals
3-5 matchup record · 4-6-0 ATS · 6-4-0 O/U
Last 10 completed games on file
Seattle Seahawks
4-4 matchup record · 4-4-2 ATS · 5-5-0 O/U
Last 10 completed games on file

Injuries and availability

From the published research (2026-11-04T04:57:32.908Z). Availability may have changed; review the cited sources.

Seattle is the winner pick, with medium confidence in the straight-up forecast. Arizona’s backfield injuries give the Seahawks a potential matchup advantage, although Seattle has unresolved personnel questions of its own. The projected 11-point margin leaves a narrow cushion for Arizona +12, too small to make that side an official wager.

Arizona’s running-back availability is the clearest concern. DK Network’s November 3 injury update lists Jeremiyah Love as TBD with an ankle injury. He was ruled out at halftime in Week 8 after returning from a two-game absence. Bam Knight is also listed as TBD and is in concussion protocol.

Those statuses leave Arizona’s options uncertain rather than confirming either player will miss the game. If both are limited or unavailable, maintaining offensive balance could become harder. That possibility favors Seattle in the forecast, but treating Arizona’s rushing attack as already depleted would overstate what the injury update says.

Recent head-to-head

  • 2026-09-20Seattle Seahawks 31 · Arizona Cardinals 7
  • 2025-11-09Arizona Cardinals 22 · Seattle Seahawks 44
  • 2025-09-25Seattle Seahawks 23 · Arizona Cardinals 20
  • 2024-12-08Seattle Seahawks 30 · Arizona Cardinals 18
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