Arizona Cardinals vs New York Giants Predictions October 4, 2026
The New York Giants will beat the Arizona Cardinals 23-20 in our forecast, with New York's 2-1 record and home field supplying a slight edge over 1-2 Arizona. Andrew Thomas' missed practices make that projection fragile, however. Neither Giants +2.5 (-103) nor either side of the 44.5-point total offers a convincing betting edge. The official recommendation is Pass, with low forecast confidence.
Arizona Cardinals vs New York Giants prediction and best bet
New York gets the outright pick because its better early record and home setting offer a modest starting point in a closely priced matchup. Those advantages deserve limited weight: three games tell only part of the story, and Arizona is the favorite at -140. This is a slight Giants lean, with no reason to expect a comfortable win.
The biggest hesitation is Thomas, who missed consecutive practices with a groin injury. His participation puts an important offensive position under scrutiny without confirming a Sunday absence. Giants +2.5 (-103) fits the forecast, but the injury uncertainty keeps it off the betting card. Best bet: Pass.
Odds, game time and how to watch
Game: Arizona Cardinals at New York Giants, Week 4 of the 2026 NFL season.
Kickoff: Sunday, October 4, 2026, at 1 p.m. ET. Broadcast: CBS.
Venue: MetLife Stadium, the Giants' third home game of the season.
Records: Cardinals 1-2; Giants 2-1.
SportsJaw moneyline: Cardinals -140; Giants +120.
SportsJaw spread: Cardinals -2.5 (-110); Giants +2.5 (-103). Arizona is the road favorite at the supplied prices despite its worse record entering this matchup on Sunday afternoon in Week 4 of the season. Both prices matter when weighing a close-game forecast against a wager.