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  1. Home
  2. NCAAF Picks
  3. Nebraska Cornhuskers vs Michigan St. Spartans
Sat 5:00 PM ET
Nebraska Cornhuskers logo
Nebraska
Cornhuskers31
3-0
versus
Michigan St. Spartans logo
Michigan St.
Spartans13
2-1
Final
Team1234T
Nebraska Cornhuskers7170731
Michigan St. Spartans373013
NCAAF · Nebraska Cornhuskers at Michigan St. Spartans

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Nebraska at Michigan State: Strong recent numbers, uncertain betting edge

Game time: September 26, 2026 at 5:00 PM ET

Venue: Spartan Stadium — East Lansing, MI

Article updated Sep 21, 4:11 AM EDT

By SportsJaw Editorial Team

Nebraska's rushing production merits attention, while Michigan State's defensive resistance at Notre Dame supplies a reason for caution.

The matchup

Nebraska visits Michigan State at Spartan Stadium on Sept. 26 in the 2026 college football season. Kickoff is scheduled for 5 p.m. Eastern, 4 p.m. Central, on BTN. The Cornhuskers enter 3-0; the Spartans are 2-1 and opening their Big Ten schedule.

SportsJaw lists Nebraska at -225 moneyline and -5.5 (-110) against the spread. Michigan State is +189 moneyline and +5.5 (-110). The total is 48.5, with over 48.5 (-110) and under 48.5 (-110).

Production needs opponent context

Nebraska beat North Dakota 34-7, gaining 493 yards and allowing 205. Jamal Rule has 329 rushing yards and five touchdowns on 38 carries through three games, averaging 8.7 yards per attempt. Anthony Colandrea completed 15 of 21 passes for 195 yards and a touchdown in the victory. Those figures give Nebraska an encouraging offensive starting point for its first road game.

Michigan State's latest performance was substantially less productive: 167 total yards, including 44 rushing, in a 27-10 loss at No. 3 Notre Dame. Alessio Milivojevic threw two interceptions while completing 9 of 17 passes for 123 yards. However, comparing that outing directly with Nebraska's win over North Dakota does not establish the same offensive gap against comparable opposition.

The Spartans also held Notre Dame below its entering average of 46.5 points. That provides a counterweight to their offensive struggles, although one result cannot establish how effectively they will contain Rule.

21+. Gambling problem? Call 1-800-GAMBLER. Picks are opinions, not guarantees. Past results do not predict future outcomes.

Betting decision

Pass. Nebraska's rushing output supports interest in the favorite, but the opponent contrast and first road assignment leave the case for laying 5.5 points fragile. The recent results also provide too little basis to estimate combined scoring reliably against 48.5. Neither a side nor a total offers a sufficiently supported recommendation, so no winner or score projection is assigned.

SportsJawGame Predictions
Predicted score

Unavailable for this preview

Projected winnerUnavailableConfidencelow
Pick on the Spread

Published pick: Pass

Pick on the Total

Published pick: Pass

Sources

  • University of Nebraska AthleticsHuskers Fight Past Hawks
  • Michigan State University AthleticsSpartans Fall at No. 3 Notre Dame, 27-10
  • Michigan State University AthleticsPost-Game Notes: Notre Dame
#NebraskaCornhuskers#MichiganStSpartans

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Written by

SportsJaw Editorial Team

SportsJaw's editorial organization researches matchup data, current odds, injuries and reporting, then validates each published preview against its listed sources and displayed markets.

About our editorial process

SportsJaw Cornhuskers vs Spartans game preview analysis and predictions incorporate current odds, injury reports, team statistics and market data. Information is updated regularly, but lines and player availability can change. Please confirm current information before wagering. View history of past Cornhuskers vs Spartans matchups or learn how our predictions work.

Current matchup data

Lines, trends and availability

Line movement since open

  • Moneyline · Nebraska Cornhuskers-205 → -225Moved
  • Moneyline · Michigan St. Spartans+170 → +189Moved
  • Spread · Nebraska Cornhuskers-5.5 (-110) → -5.5 (-115)Moved
  • Spread · Michigan St. Spartans+5.5 (-110) → +5.5 (-105)Moved
  • Total · Over52.5 (-112) → 48.5 (-115)Moved
  • Total · Under52.5 (-108) → 48.5 (-105)Moved

ATS and O/U trends

Nebraska Cornhuskers
3-0 matchup record · 4-5-1 ATS · 7-3-0 O/U
Last 10 completed games on file
Michigan St. Spartans
2-1 matchup record · 7-2-1 ATS · 4-6-0 O/U
Last 10 completed games on file

Injuries and availability

From the published research (2026-09-19T05:57:07.854Z). Availability may have changed; review the cited sources.

No verified injury or availability note was included in the published matchup research.

Recent head-to-head

  • 2025-10-04Michigan St. Spartans 27 · Nebraska Cornhuskers 38
  • 2023-11-04Nebraska Cornhuskers 17 · Michigan St. Spartans 20
Final result

Matchup pick recap

Nebraska Cornhuskers defeated Michigan St. Spartans 31-13

Nebraska Cornhuskers defeated Michigan St. Spartans 31-13 on September 26, 2026, a 18-point decision in the series. Nebraska Cornhuskers' strongest period was the 2nd quarter, when it outscored its opponent 17-7. Against SportsJaw's recorded Nebraska Cornhuskers -5.5 (-115) spread, Nebraska Cornhuskers covered, while the 44 combined points finished under the recorded total of 48.5.

SportsJaw editorial picks

  • Projected winnerNo published selectionUnavailable
  • SpreadPassPass
  • TotalPassPass

Tipster picks

  • ThetotalerSpread · Nebraska Cornhuskers +5.5 (-110)Win
  • GustavosintoSpread · Nebraska Cornhuskers -5.5 (-110)Win