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  1. Home
  2. NCAAF Picks
  3. USC Trojans vs Indiana Hoosiers
Sat 3:30 PM ET
USC Trojans logo
USC
Trojans
7-2
versus
Indiana Hoosiers logo
Indiana
Hoosiers
6-1
NCAAF · USC Trojans at Indiana Hoosiers

Your Picks on USC vs Indiana

Picks close 15 minutes before game time (ET)
Spread
Moneyline
Total

USC vs Indiana consensus picks

USC Trojans61%
39%Indiana Hoosiers
Odds comparison

Sportsbook lines for this game

Current lines

MatchupBest availableDraftKingsFanDuelBetMGMBet105BetOnlineHeritageLowvigPinnacleSportsbettingUnibetYouWagertheScore Bet
Nov 14, 3:30 PM ETUSC TrojansIndiana Hoosiers
Best available+243Pinnacle-265FanDuel
DraftKings——
FanDuel+215-265BEST
BetMGM+230-285
Bet105——
BetOnline+234-285
Heritage+231-287
Lowvig+234-285
Pinnacle+243BEST-299
Sportsbetting+234-285
Unibet+220-286
YouWager——
theScore Bet+230-280

USC Trojans vs Indiana Hoosiers Prediction, Odds and Best Bet for Nov. 14, 2026

Game time: November 14, 2026 at 3:30 PM ET

Venue: Memorial Stadium (Bloomington, IN) — Bloomington, IN

Article updated Nov 9, 10:06 AM EST

By SportsJaw Editorial Team

Indiana is our projected winner, Indiana 28, USC 21, with the passing matchup highlighted by College Football Charts supplying the strongest analytical reason. That advantage remains another analyst’s assessment, and the forecasts differ meaningfully on the winning margin. At the supplied SportsJaw prices, neither USC +7.5 (-115) nor the 49.5 total offers a persuasive wagering edge. The official recommendation is Pass.

USC Trojans vs Indiana Hoosiers prediction and best bet

Pick Indiana to win, but pass on the betting markets. College Football Charts, Blue Chip Analytics and Dimers all favor the Hoosiers outright in this 2026 college football matchup. Their agreement helps shape our forecast; it does not make Indiana a certain winner or turn either spread side into a value bet.

The distinction matters at Indiana -7.5 (-105). The published margins range from seven to 13 points, crossing the threshold needed for a Hoosiers cover. Our Indiana 28, USC 21 forecast lands on the closer end of that range. Confidence is low because the detailed matchup case rests on outside predictions, while the accepted non-prediction reporting chiefly confirms the fixture and records.

Odds, game time and how to watch

Game: USC Trojans at Indiana Hoosiers, 2026 NCAAF season.

Kickoff: November 14, 2026, at 3:30 p.m. ET, as listed by Covers.

Records: USC Trojans 7-2; Indiana Hoosiers 6-1.

SportsJaw odds: USC Trojans +7.5 (-115); Indiana Hoosiers -7.5 (-105). Moneyline: USC Trojans +234; Indiana Hoosiers -285. Total: Over 49.5 (-109); Under 49.5 (-109).

SportsJaw total: Over 49.5 (-110); Under 49.5 (-110).

21+. Gambling problem? Call 1-800-GAMBLER. Picks are opinions, not guarantees. Past results do not predict future outcomes.

SportsJaw moneyline: USC +230; Indiana -280.

USC Trojans outlook

USC brings a 7-2 record into the visit, but the most specific concern comes from College Football Charts’ analysis. That outlet describes a matchup between USC’s 115th-ranked rushing offense and Indiana’s fifth-ranked yards-per-carry defense. Those rankings are part of its prediction rationale, rather than independently corroborated team statistics here.

If that assessment is right, USC’s route to a competitive finish would require production despite a difficult rushing matchup. Dimers offers the more encouraging outlook for the Trojans, projecting a 28-21 loss and assigning USC +7.5 a 50.3% chance to cover. That is a plausible close-game scenario, though its tiny probability advantage is insufficient compensation for the -115 price.

Indiana Hoosiers outlook

Indiana’s 8-1 record gives the Hoosiers the better record entering this matchup. College Football Charts favors them 33-20 with a 71% win probability. Its passing-game argument compares Indiana’s No. 11 adjusted passing EPA ranking with USC’s No. 106 pass-defense ranking. We treat that comparison as the outlet’s explanation for its pick.

Blue Chip Analytics also prefers Indiana, projecting an 8.8-point margin. Its analysis uses a 5.6-point neutral-field rating advantage and adjustments for home field and USC’s travel. Those are model judgments, not measured points Indiana can count on receiving. Its forecast is less comfortable for favorite backers than College Football Charts’ 13-point margin.

Key matchup factors

The central question is how much of the analysts’ proposed Indiana advantage reaches the scoreboard. College Football Charts anticipates enough separation for a clear cover. Blue Chip sees a narrower cover, while Dimers’ seven-point margin leaves USC inside the supplied spread. Their shared winner masks a meaningful betting disagreement.

The November 9 SportsJaw consensus snapshot, updated at 14:51 UTC, shows external support of 60% for USC against the spread and 68% for the Under. Its external moneyline preference is Indiana at 87%. These selection percentages are distinct from win probabilities and SportsJaw member picks. They suggest a popular Indiana-win, USC-cover combination, without proving it is profitable.

Dimers’ 72.2% Indiana win probability belongs to its own model. It is neither the consensus percentage nor our confidence rating. An outright Indiana selection and a slight USC spread preference are compatible outcomes, not contradictory predictions.

USC Trojans vs Indiana Hoosiers spread prediction

Spread recommendation: Pass on USC +7.5 (-115) and Indiana -7.5 (-105). USC’s hook matters to our seven-point forecast, but a projected score alone is too narrow a foundation for an official wager.

At -115, USC needs a cover rate above approximately 53.5% to break even. Dimers’ 50.3% estimate falls short. Meanwhile, the larger Indiana margins from College Football Charts and Blue Chip supply a credible opposing case. Blue Chip’s cited comparison line was Indiana -7.0; our evaluation uses the supplied -7.5 (-105). Consensus support does not settle that disagreement.

USC Trojans vs Indiana Hoosiers total prediction

Total recommendation: Pass on Over 49.5 (-110) and Under 49.5 (-110). Our projection totals 49 points, leaving only half a point beneath the line. That small gap is not a convincing Under edge.

The outside forecasts also straddle the number: Dimers projects 49 combined points, while College Football Charts projects 53. External consensus favors the Under, but that preference is not a calibrated probability of cashing an Under ticket. Neither direction earns an official recommendation.

USC Trojans vs Indiana Hoosiers Projected Score & Betting Picks

Game forecast: Indiana 28, USC 21. Indiana gets the outright selection because the accepted analysts consistently favor it, with College Football Charts offering the clearest matchup explanation. The strongest caution is the limited independent statistical corroboration, alongside substantial disagreement about the margin.

Confidence: Low. The forecast describes our expected result, not a promised finish or a demonstrated betting edge. Both the spread and total remain passes at the supplied prices. Official SportsJaw wager: Pass.

SportsJawGame Predictions
Predicted score

Trojans21

Hoosiers28

Projected winner Indiana HoosiersConfidencelow
Pick on the Spread

Published pick: Pass on USC Trojans +7.5 (-115) and Indiana Hoosiers -7.5 (-105)

Pick on the Total

Published pick: Pass on Over 49.5 (-110) and Under 49.5 (-110)

Sources

  • CoversUSC Trojans vs Indiana Hoosiers Odds & Betting Lines For November 14, 2026 - NCAAF
  • College Football ChartsUSC vs. Indiana Prediction and Pick, Week 11 2026
  • Blue Chip AnalyticsUSC vs Indiana Prediction, Odds & Weather | Nov 14
#USCTrojans#IndianaHoosiers

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Written by

SportsJaw Editorial Team

SportsJaw's editorial organization researches matchup data, current odds, injuries and reporting, then validates each published preview against its listed sources and displayed markets.

About our editorial process

SportsJaw Trojans vs Hoosiers game preview analysis and predictions incorporate current odds, injury reports, team statistics and market data. Information is updated regularly, but lines and player availability can change. Please confirm current information before wagering. View history of past Trojans vs Hoosiers matchups or learn how our predictions work.

Current matchup data

Lines, trends and availability

Line movement since open

  • Moneyline · USC Trojans+330 → +234Moved
  • Moneyline · Indiana Hoosiers-425 → -285Moved
  • Spread · USC Trojans+10 (-110) → +7.5 (-115)Moved
  • Spread · Indiana Hoosiers-10 (-110) → -7.5 (-105)Moved
  • Total · Over58.5 (-110) → 49.5 (-109)Moved
  • Total · Under58.5 (-110) → 49.5 (-109)Moved

ATS and O/U trends

USC Trojans
7-2 matchup record · 3-7-0 ATS · 5-5-0 O/U
Last 10 completed games on file
Indiana Hoosiers
6-1 matchup record · 3-7-0 ATS · 5-5-0 O/U
Last 10 completed games on file

Injuries and availability

From the published research (2026-11-08T05:32:32.941Z). Availability may have changed; review the cited sources.

No verified injury or availability note was included in the published matchup research.

Recent head-to-head

No completed head-to-head result is available in the current history window.

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