Florida St. Seminoles vs Louisville Cardinals prediction, odds and projected score for October 9
Louisville is projected to beat Florida State 31-28, with its balanced offense and efficient quarterback play providing the strongest reason to favor the Cardinals. Florida State’s recent defensive dominance makes this a low-confidence forecast, however. Neither Louisville -3.5 (-109), Florida State +3.5 (-105), nor the 59.5 total offers a convincing betting edge. The official recommendation is Pass.
Florida St. Seminoles vs Louisville Cardinals prediction and best bet
Louisville gets the win prediction because its offensive production extends across five games and includes substantial contributions through the air and on the ground. That balance offers a plausible answer to Florida State’s disruptive front. The forecast is Louisville 31, Florida State 28.
Florida State’s performance against Virginia makes the decision close. The Seminoles have a credible route to an upset through quarterback Ashton Daniels and defensive pressure. Louisville’s broader offensive record earns a slight preference, but the supplied prices leave the best-bet decision at Pass.
Odds, game time and how to watch
Game time: Friday, October 9, 2026, at 7 p.m. ET, in the 2026 college football season.
Venue: L&N Federal Credit Union Stadium, Louisville.
Broadcast: ESPN.
Records and streaks: Florida State is 3-2 overall and 1-1 in ACC play after wins over Central Arkansas and Virginia. Louisville is 2-3 following consecutive defeats, most recently 31-28 at NC State on October 3.
SportsJaw odds: Florida St. Seminoles +4 (-110); Louisville Cardinals -4 (-110). Moneyline: Florida St. Seminoles +160; Louisville Cardinals -185. Total: Over 60.5 (-110); Under 60.5 (-110).