Colorado Buffaloes vs Oklahoma St. Cowboys Predictions October 24, 2026
Oklahoma State will beat Colorado, with a projected score of Oklahoma State 31, Colorado 24. Drew Mestemaker’s five consecutive 300-yard passing games give the Cowboys the strongest sustained offensive evidence entering this matchup. Colorado’s competitive performance against Utah makes the large spread less appealing, but neither Colorado +14.5 (-122) nor the 54.5 total offers a convincing wager. The official recommendation is Pass.
Colorado Buffaloes vs Oklahoma St. Cowboys prediction and best bet
Oklahoma State is the pick to win this October 24 college football matchup. Mestemaker’s production across five games gives the Cowboys a stronger foundation for the forecast than a single encouraging performance. Returning to Boone Pickens Stadium also puts their next opportunity at home after a narrow road defeat.
The best betting decision is Pass. Colorado showed enough offense against Utah to make taking 14.5 points tempting, but one close loss is a thin foundation for a wager carrying a -122 price. Oklahoma State’s uneven performance at Houston also makes its -14.5 (+100) difficult to endorse. The projected seven-point margin is a low-confidence forecast, not a measured betting edge.
Odds, game time and how to watch
Date and competition: Saturday, October 24, 2026, during the 2026 college football season.
Venue: Boone Pickens Stadium.
Records: Colorado Buffaloes 2-4; Oklahoma St. Cowboys 3-2.
SportsJaw moneyline: Colorado +450; Oklahoma State -630.
SportsJaw odds: Colorado Buffaloes +13.5 (-106); Oklahoma St. Cowboys -13.5 (-115). Moneyline: Colorado Buffaloes +430; Oklahoma St. Cowboys -625. Total: Over 55.5 (-108); Under 55.5 (-112).