| Score | Moneyline | Spread | Game total | |
|---|---|---|---|---|
| Michigan St. SpartansMICHST | 13 | +1450 L | +26.5 (-110) W | O 49.5 (-110) W U 49.5 (-110) L |
| Indiana HoosiersINDIAN | 38 | -4000 W | -26.5 (-110) L |
Indiana Hoosiers defeated Michigan St. Spartans 38-13
Indiana Hoosiers defeated Michigan St. Spartans 38-13 on October 18, 2025, a 25-point decision in the series. Indiana Hoosiers' strongest period was the 3rd quarter, when it outscored its opponent 14-0. Against SportsJaw's recorded Michigan St. Spartans +26.5 (-110) spread, Michigan St. Spartans covered, while the 51 combined points finished over the recorded total of 49.5.
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