Missouri Tigers vs Mississippi Rebels prediction, odds and best bet for Oct. 17, 2026
Missouri will beat Mississippi 31-27 in our forecast for October 17, with Jamal Roberts’ rushing production giving the Tigers their strongest advantage against the Rebels’ vulnerable run defense. Missouri +5.5 (-110) is the official spread wager at the supplied SportsJaw price. Confidence is medium, with Ole Miss’ recent defensive improvement a meaningful concern. Pass on the total of 58.5 (-110).
Missouri Tigers vs Mississippi Rebels prediction and best bet
Missouri’s case starts with a favorable matchup on the ground and extends to its ability to defend the run. That combination makes the Tigers an appealing underdog, even against a higher-ranked Ole Miss team playing at home. The forecast is a Missouri upset, with Missouri +5.5 (-110) the best bet.
The spread offers room for the outright prediction to miss narrowly. A Missouri loss by five points or fewer would still cash the ticket. That protection matters because the Rebels bring a productive quarterback and a defense that showed improvement in its last game. This is a supported edge, with enough resistance to keep confidence at medium.
Odds, game time and how to watch
Game: Missouri Tigers at Mississippi Rebels, 2026 college football season.
Kickoff: Saturday, October 17, 2026, at 2:30 p.m. CT, according to the official Ole Miss previews.
Venue: Vaught-Hemingway Stadium in Oxford, Mississippi.
Broadcast: SEC Network.
Records and rankings: No. 13 Missouri is 5-1 overall and 2-1 in SEC play. No. 9 Ole Miss is 4-1 overall and 2-1 in the SEC.
SportsJaw odds: Missouri Tigers +4 (-110); Mississippi Rebels -4 (-108). Moneyline: Missouri Tigers +155; Mississippi Rebels -180. Total: Over 57.5 (-108); Under 57.5 (-110).