Penn St. Nittany Lions vs Michigan Wolverines Prediction, Odds and Best Bet for October 17, 2026
Michigan will beat Penn State 24-17, with home field and the Nittany Lions’ struggling rushing attack providing the strongest reasons to favor the Wolverines. Michigan’s own recent offensive difficulties keep confidence low, however. Neither Michigan -7 (-105) nor the 42.5-point total offers a convincing betting edge, so the official SportsJaw recommendation is Pass.
Penn St. Nittany Lions vs Michigan Wolverines prediction and best bet
Michigan gets the winner pick, but neither team enters with a Big Ten victory. Penn State’s recent trouble running the ball makes the road upset harder to project, while Michigan’s limited production in its last game argues against expecting a comfortable win.
The best betting decision is Pass. A Michigan 24, Penn State 17 forecast lands exactly on the seven-point spread and only 1.5 points below the total. Those narrow margins leave little room for an inaccurate projection, especially with both offenses presenting questions.
Odds, game time and how to watch
Game time: Saturday, October 17, 2026, at 3:30 p.m. ET.
Venue: Michigan Stadium.
Broadcast: CBS.
Records: Penn St. Nittany Lions 2-3; Michigan Wolverines 2-2.
SportsJaw moneylines: Penn State +211; Michigan -255.
SportsJaw spreads: Penn State +7 (-115); Michigan -7 (-105). Total: Over 42.5 (-108); Under 42.5 (-110).
Penn St. Nittany Lions outlook
Penn State’s ground game is the clearest concern. The Nittany Lions rushed for 48 yards in their October 2 loss at Northwestern and averaged 2.2 yards per carry against USC on October 10. Another inefficient rushing performance would increase the burden on a receiving group missing Koby Howard.

