Mississippi Rebels vs Vanderbilt Commodores Prediction, Odds and Best Bet for October 10, 2026
Mississippi will beat Vanderbilt, 31-24, with Trinidad Chambliss’ efficient passing providing the strongest edge. Vanderbilt’s productive pass rush and Mississippi’s tackling problems make Vanderbilt +9.5 (-110) the best bet at the supplied price. The Rebels get the outright call with medium confidence, while the total of 54.5 (-110) is a Pass because the forecast leaves almost no scoring cushion.
Mississippi Rebels vs Vanderbilt Commodores prediction and best bet
The pick is Mississippi to win, with Vanderbilt +9.5 (-110) as the official spread wager. Chambliss gives the Rebels a persuasive offensive advantage, but their documented tackling problems make a comfortable victory less certain. Vanderbilt has a credible path to stay inside the number through defensive pressure and enough offense to answer.
This is a bet on a competitive margin, with meaningful risk attached. Vanderbilt’s quarterback availability and penalty rate could undermine the cover. Still, its sack production offers a specific way to interrupt Mississippi possessions, and getting more than a touchdown leaves room for the Rebels to control the result without covering.
Odds, game time and how to watch
Game time: Saturday, October 10, 2026, at 2:30 p.m. CT.
Venue: FirstBank Stadium in Nashville, Tennessee.
Broadcast: ESPN.
Records: Mississippi Rebels 2-1; Vanderbilt Commodores 3-2.
SportsJaw moneyline: Mississippi -350; Vanderbilt +281.
SportsJaw odds: Mississippi Rebels -9.5 (-110); Vanderbilt Commodores +9.5 (-110). Moneyline: Mississippi Rebels -350; Vanderbilt Commodores +287. Total: Over 54.5 (-115); Under 54.5 (-105).

