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NCAAF PicksSat 7:30 PM ET
USC Trojans logo
USC
Trojans
5-1
versus
Penn St. Nittany Lions logo
Penn St.
Nittany Lions
2-2
NCAAF · USC at PENNST

Your Picks on USC vs Penn St.

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USC vs Penn St. consensus picks

USC74%
26%PENNST

USC Trojans vs Penn St. Nittany Lions Predictions October 10, 2026

Game time: October 10, 2026 at 7:30 PM ET

Venue: Beaver Stadium — University Park, PA

Article updated Oct 8, 11:45 AM EDT

By SportsJaw Editorial Team

USC will beat Penn State 30-24, with its efficient passing attack and King Miller’s rushing production offering the strongest matchup advantage against a defense coming off a difficult afternoon at Northwestern. USC +1.5 (-110) is the best bet at the supplied price. Confidence is medium because Penn State’s season-long defensive numbers remain strong. Pass on the total of 54.5.

USC Trojans vs Penn St. Nittany Lions prediction and best bet

USC +1.5 (-110) is the selection because the Trojans have two credible ways to sustain drives: Jayden Maiava’s passing and Miller’s work on the ground. Their offensive production makes taking the points attractive even against a Penn State defense with impressive season averages.

The forecast favors USC 30, Penn State 24. Northwestern’s rushing success gives USC a weakness to attack, but one game should not erase Penn State’s broader defensive performance. That tension keeps confidence at medium and makes the spread a stronger choice than the total.

Odds, game time and how to watch

Game time: Saturday, October 10, 2026, at 7:30 p.m. ET / 4:30 p.m. PT. This is a 2026 college football matchup between visiting USC and Penn State.

Venue: Beaver Stadium, University Park, Pennsylvania.

Broadcast: NBC.

Records: USC is 5-1 overall and 2-1 in Big Ten play. Penn State is 3-2 overall and 0-2 in conference play, with consecutive losses to Wisconsin and Northwestern.

SportsJaw odds: USC +1.5 (-110); Penn State -1.5 (-110). Moneyline: USC +100; Penn State -120. Total: Over 54.5 (-112), Under 54.5 (-105).

Consensus: As of October 8 at 15:32 UTC, SportsJaw’s combined consensus favored USC +100 at 72 percent, up one percentage point from October 7. Over 54.5 (-112) led the total at 80 percent. These blended percentages are separate from team win probabilities; neither market has a separate SportsJaw member-pick leader reported.

USC Trojans outlook

USC enters with an offense averaging 37.3 points and 467.8 yards through six games, including 311.7 passing yards. Maiava has completed 131 of 191 attempts for 1,744 yards, 15 touchdowns and three interceptions. His production gives the Trojans a credible passing threat even if Penn State makes rushing yards difficult to find.

Miller supplies the complementary threat with 493 rushing yards on 95 carries, averaging 5.2 yards. He gained 81 yards on 18 attempts in the October 3 win over Washington. USC rallied from a 21-10 third-quarter deficit to win 25-21, holding Washington scoreless over the final 28:30.

The October 7 availability report listed starting tight end Mark Bowman and starting defensive tackle Jide Abasiri as questionable. Receiver Corey Simms, safety Kendarius Reddick, linebacker Roman Marchetti and offensive lineman Kilian O'Connor were out. Bowman’s uncertainty matters to the offensive outlook, while Abasiri’s status adds uncertainty to USC’s defensive front.

Penn St. Nittany Lions outlook

Penn State’s strongest counterargument is its defensive record through five games: 16.0 points and 292.8 yards allowed per game, including 119.6 passing yards. Those numbers warrant respect against a USC offense that gets substantial production through the air.

The concern is how sharply the October 3 loss at Northwestern departed from that baseline. Northwestern rushed for 413 yards on 55 carries in a 34-13 victory. Penn State struggled to generate its own rushing production, with Carson Hansen leading the team that afternoon with 19 yards.

Rocco Becht completed 26 of 41 passes for 243 yards and a touchdown in that loss. Through five games, he has 1,108 passing yards, 10 touchdowns and three interceptions. Penn State has a passing route to a rebound, but a stronger ground contribution would make that task easier.

The October 7 report listed rotational defenders Alex Tatsch and Armstrong Nnodim as questionable. Center Brock Riker was absent from the report, although coach Matt Campbell said he had been playing through an injury. Backup Vaea Ikakoula replaced Riker in the fourth quarter against Northwestern.

Key matchup factors

Third down brings the clearest clash of strengths. USC has converted 37 of 71 attempts, or 52.1 percent, through six games. Penn State has held opponents to 23 percent through five. USC’s ability to extend possessions is central to this forecast, but Penn State has a substantial statistical counter.

Early-down rushing success could decide which strength wins out. If Miller creates manageable distances, USC can keep both running and passing options open. If Penn State forces obvious passing situations, its strong pass-defense numbers become more relevant.

The consensus preference for USC aligns with the pick, but it is not a second measure of offensive quality. The football case rests on USC’s production and the opportunity to test Penn State’s run defense, with the Nittany Lions’ broader defensive record keeping the edge ordinary.

USC Trojans vs Penn St. Nittany Lions spread prediction

Take USC Trojans +1.5 (-110). The outright forecast favors USC, and the spread also covers a one-point Penn State victory. A two-point loss would lose the bet, so this is a small cushion rather than broad protection.

Penn State -1.5 (-110) has a credible case if its defense returns to its season baseline. Still, USC’s demonstrated passing efficiency and useful rushing option make the visiting side preferable at these prices. The recommendation carries medium confidence.

USC Trojans vs Penn St. Nittany Lions total prediction

Pass on Over 54.5 (-112) and Under 54.5 (-105). The projected 54 points sit only half a point below the line, too narrow a margin to turn the score forecast into an Under recommendation.

USC’s scoring average favors a productive offensive game, while Penn State’s defensive averages argue for restraint. The strong Over consensus reflects betting preference, not a scoring projection. Neither direction offers as convincing a case as USC plus the points.

USC Trojans vs Penn St. Nittany Lions projected score

Game forecast: USC 30, Penn State 24. Maiava’s passing and Miller’s rushing give USC the better route to sustained offense. The strongest counterargument is Penn State’s ability to limit passing yards and end possessions on third down.

Confidence is medium, with the questionable USC starters adding uncertainty. The single official SportsJaw wager is spread: USC Trojans +1.5 (-110). The total remains a Pass.

SportsJawGame Predictions
Predicted score

USC30

PENNST24

Projected winner USC TrojansConfidenceStrong Lean — USC Trojans
Pick on the Spread

Strong Lean — USC Trojans +1.5

Editorial pick at publication: Spread: USC Trojans +1.5 (-110)

Pick on the Total

Slight Lean — Under 54.5

Editorial pick at publication: Pass on Over 54.5 (-112) and Under 54.5 (-105)

Sources

  • USC AthleticsNo. 19 USC Football Set To Brace 'White Out' Environment At Penn State For Primetime Showdown
  • StateCollege.com2 Penn State Defenders Questionable Against USC: Full Availability Report
  • Penn State AthleticsPrevious-game context: Penn State Drops Road Test at Northwestern, 34-13

SportsJaw Trojans vs Nittany Lions game preview analysis and predictions incorporate current odds, injury reports, team statistics and market data. Information is updated regularly, but lines and player availability can change. Please confirm current information before wagering. View history of past Trojans vs Nittany Lions matchups or learn how our predictions work.

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