USC Trojans vs Penn St. Nittany Lions Predictions October 10, 2026
USC is projected to beat Penn State 27-24 on Oct. 10, 2026, with its defensive finish against Washington providing the strongest recent reason to favor the Trojans. Penn State’s takeaway production offers a credible counterweight at home. Confidence is low, and neither USC +1.5 (-110) nor the total of 58.5 (-110) offers a sufficiently clear edge for an official wager.
USC Trojans vs Penn St. Nittany Lions prediction and best bet
USC gets the narrow nod after completing a comeback against Washington, while Penn State enters this matchup following a 21-point loss at Northwestern. The Trojans’ latest defensive finish tips the forecast their way, but comparing two games against different opponents leaves considerable uncertainty.
The official betting decision is Pass. USC’s recent result makes it the editorial choice to win; it does not make the Trojans an automatic bargain as a small underdog. Penn State’s ability to generate takeaways is a meaningful threat to that projection.
Odds, game time and how to watch
Game: USC Trojans at Penn St. Nittany Lions, Oct. 10, 2026, in the 2026 college football season.
Venue: West Shore Home Field at Beaver Stadium. Penn State has designated this matchup as its White Out.
Records: USC enters at 5-1 overall and 2-1 in Big Ten play. Penn State is 3-2 overall and 0-2 in conference play.
SportsJaw spread and moneyline: USC +1.5 (-110) and +102; Penn State -1.5 (-110) and -124.
SportsJaw total: Over 58.5 (-110) or Under 58.5 (-110).
USC Trojans outlook
USC beat Washington 25-21 on Oct. 3 after trailing 21-10 in the second half. The Trojans scored the final 15 points, held Washington scoreless in the fourth quarter and ended its last threat with a fourth-down stop. That recovery supports the forecast, although needing a comeback also keeps the performance in perspective.