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  1. Home
  2. MLB Picks
  3. Washington Nationals vs St. Louis Cardinals
Sat 7:15 PM ET
Washington Nationals logo
Washington
Nationals8
A. Alvarez LHP
versus
St. Louis Cardinals logo
St. Louis
Cardinals5
M. McGreevy RHP
Final/11
Team1234567891011T
Washington Nationals200001000148
St. Louis Cardinals

Nationals vs. Cardinals: Washington a slight moneyline lean

Game time: September 19, 2026 at 7:15 PM ET

Venue: Busch Stadium — St. Louis, Missouri

Article updated Sep 19, 9:42 AM EDT

By SportsJaw Editorial Team

Washington's offensive production makes the underdog appealing, but McGreevy's latest start and the Nationals' road record temper confidence.

Matchup and pitching

The Washington Nationals visit the St. Louis Cardinals on September 19 in this 2026 MLB matchup, with Andrew Alvarez and Michael McGreevy listed as the probable starters. SportsJaw prices Washington at +110 and St. Louis at -130 on the moneyline.

Alvarez brings a 3.35 season ERA and 1.27 WHIP. His September 12 outing against the Angels was strong: seven innings, one hit, no runs and eight strikeouts. Four walks provide a caution, however. Another start with that many free passes could create scoring opportunities.

McGreevy has a higher season ERA at 3.83 but a slightly lower WHIP at 1.24. He allowed one earned run in six innings against the White Sox on September 13. His seven earned runs over five innings against Baltimore on August 26 show a less favorable outcome, but his latest performance is meaningful counterevidence to backing Washington.

Offense and price

Washington averages 5.11 runs per game against St. Louis' 4.51, and its .426 slugging percentage ranks second in the National League. Those numbers support taking the Nationals at an underdog price.

Recent and location-specific results make the advantage less decisive. Washington is 5-5 over its last 10 games, batting .229, and 35-41 on the road. St. Louis is 37-42 at home and has gone 3-7 over its last 10 while hitting .217. Washington's 9-1 series-opening win adds context, but one result carries limited predictive weight.

Final prediction

The selection is Washington Nationals moneyline (+110), with low confidence and a projected 5-4 Washington win. The offensive advantage and Alvarez's season ERA support a slight lean.

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MLB · Washington Nationals at St. Louis Cardinals

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21+. Gambling problem? Call 1-800-GAMBLER. Picks are opinions, not guarantees. Past results do not predict future outcomes.

That projection totals nine runs against SportsJaw's 8.5 line, priced over 8.5 (-116) and under 8.5 (+101). The narrow margin and both starters' strong latest outings leave insufficient conviction for a total wager.

SportsJawGame Predictions
Predicted score

Nationals5

Cardinals4

Projected winner Washington NationalsConfidencelow
Pick on the Spread

Published pick: Unavailable

Pick on the Total

Published pick: Unavailable

Pick on the Moneyline

Published pick: Washington Nationals moneyline (+110)

Sources

  • CoversNationals vs Cardinals Game Overview, Stats, Injuries, Records - MLB Game on September 19, 2026
  • FOX Sports / Associated PressCardinals aim to end losing streak in game against the Nationals
#WashingtonNationals#StLouisCardinals

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Written by

SportsJaw Editorial Team

SportsJaw's editorial organization researches matchup data, current odds, injuries and reporting, then validates each published preview against its listed sources and displayed markets.

About our editorial process

SportsJaw Nationals vs Cardinals game preview analysis and predictions incorporate current odds, injury reports, team statistics and market data. Information is updated regularly, but lines and player availability can change. Please confirm current information before wagering. View history of past Nationals vs Cardinals matchups or learn how our predictions work.

Current matchup data

Lines, trends and availability

Line movement since open

  • Moneyline · Washington Nationals+110 → -107Moved
  • Moneyline · St. Louis Cardinals-130 → -103Moved
  • Spread · Washington Nationals+1.5 (-200) → +1.5 (-210)Moved
  • Spread · St. Louis Cardinals-1.5 (+165) → -1.5 (+180)Moved
  • Total · Over8.5 (-120) → 8.5 (-118)Moved
  • Total · Under8.5 (+100) → 8.5 (-102)Moved

ATS and O/U trends

Washington Nationals
63-71 matchup record · 4-6-0 ATS · 7-3-0 O/U
Last 10 completed games on file
St. Louis Cardinals
62-69 matchup record · 4-6-0 ATS · 7-3-0 O/U
Last 10 completed games on file

Injuries and availability

From the published research (2026-09-19T04:58:27.693Z). Availability may have changed; review the cited sources.

No verified injury or availability note was included in the published matchup research.

Recent head-to-head

  • 2026-09-18Washington Nationals 9 · St. Louis Cardinals 1
Final result

Matchup pick recap

Washington Nationals defeated St. Louis Cardinals 8-5

Washington Nationals defeated St. Louis Cardinals 8-5 on September 19, 2026, a 3-run decision in the series. Washington Nationals' strongest period was the 11th inning, when it outscored its opponent 4-1. Against SportsJaw's recorded Washington Nationals +1.5 (-210) spread, Washington Nationals covered, while the 13 combined runs finished over the recorded total of 8.5.

SportsJaw editorial picks

  • Projected winnerWashington NationalsWin
  • MoneyWashington Nationals moneyline (+110)Win

Tipster picks

  • 1188460207Moneyline · Washington Nationals +110Win
  • JohnmiznerMoneyline · Washington Nationals +110Win
  • CodexMoneyline · Washington Nationals +110Win