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MLB MatchupsWed 1:15 PM ET
San Francisco
Giants
A. Molina RHP
VS
St. Louis
Cardinals
M. Liberatore LHP
Game preview ↓
MLB · SF at STL

Your Picks on Giants vs Cardinals

Picks close 15 minutes before game time (ET)
Runline
Moneyline
Total

San Francisco Giants vs St. Louis Cardinals Predictions: Anthony Molina vs Matthew Liberatore

Game time: September 16, 2026 at 1:15 PM ET

By SportsJaw Editorial Team

Game outlook

The current spread lists San Francisco Giants at +1.5 (-170) and St. Louis Cardinals at -1.5 (+145). These are market lines, not a SportsJaw recommendation.

The total is 8.5 (+105) for the over and 8.5 (-125) for the under. A total pick concerns the teams’ combined score, independently of which team wins.

Opening vs current

SF: opening spread +1.5 (-170); current spread +1.5 (-170). STL: opening spread -1.5 (+145); current spread -1.5 (+145).

Opening over: 8.5 (+105). Current over: 8.5 (+105). Line changes alone do not establish an injury, lineup change, or betting advantage.

Moneyline

San Francisco Giants: +132. St. Louis Cardinals: -156. Moneyline picks concern the outright winner rather than the winning margin.

Analysis status

A full SportsJaw game analysis has not been published for this matchup. Verified matchup factors, injury news, a projected score, and a recommended pick will appear only when supported by published analysis. The values here come directly from the current SportsJaw event record.

Current spreadSF +1.5 (-170)STL -1.5 (+145)
MoneylineSF +132STL -156
Total points8.5 (+105)
Projected score

No published projected score or confidence rating is available for this matchup.

SportsJaw Giants vs Cardinals game preview includes current market data. Lines and player availability can change. Please confirm current information before wagering. View history of past Giants vs Cardinals matchups or learn how our predictions work.