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  1. Home
  2. MLB Picks
  3. Chicago Cubs vs St. Louis Cardinals
Fri 8:15 PM ET
Chicago Cubs logo
Chicago
Cubs0
M. Boyd LHP
versus
St. Louis Cardinals logo
St. Louis
Cardinals5
M. McGreevy RHP
Final
Team123456789T
Chicago Cubs0000000000
St. Louis Cardinals01002200—

Chicago Cubs vs St. Louis Cardinals Betting Picks & Predictions

Game time: August 8, 2025 at 8:15 PM ET

Venue: Busch Stadium — St. Louis, Missouri

Article updated Aug 8, 11:47 PM EDT

Published by SportsJaw Editorial Team

On Friday, August 8th, the Chicago Cubs will face off against the St. Louis Cardinals in a highly anticipated National League rivalry matchup. The Cubs currently hold the top

Game outlook

On Friday, August 8th, the Chicago Cubs will face off against the St. Louis Cardinals in a highly anticipated National League rivalry matchup. The Cubs currently hold the top record in the wild card race with a 66-48, while the Cardinals are 58-58 and are at least six games back of a playoff spot. The Cubs have won four of their last seven games, while the Cardinals have struggled, losing seven of their last 11. Matthew Boyd will start for the Cubs and Michael McGreevy will start for the Cardinals. The first pitch is scheduled for 8:15 P.M. EST. Be sure to read our prediction for this game and other top MLB picks.

Betting Odds

Moneyline: Cubs -165 | Cardinals +147

Spread: Cubs -1.5 (+100) | Cardinals +1.5 (-120)

Total: Over/Under 8.5 (-110)

Based on the moneyline, the implied probability that Chicago will win straight-up is 62%.

Chicago Cubs

The Chicago Cubs are currently 89-73 overall this season, sitting in second place in the National League Central division behind the Brewers by four games. They hold the top spot in the wild card race, seven games ahead of the Reds. The Cubs have a 30-26 record when playing on the road and have won four of their last seven games. Chicago is 4-3 against the Cardinals this year. In their last game, the Cubs defeated the Reds 6-1 on Wednesday, Aug. 6 to avoid being swept. On Friday, the Cubs will have Matthew Boyd on the mound against the Cardinals. Boyd, an 11-4 left-handed pitcher with a 2.34 ERA in 22 starts, is coming off a strong 7.0 inning performance allowing zero runs and four hits in a 4-3 loss to the Orioles on Aug. 2. The Cubs are 12-10 in games started by Boyd this season. When pitching on the road, Boyd has a 2.97 ERA in 11 starts. The Cubs have a .253 team batting average, ranking eighth in the league, with the second most runs scored and sixth most hits. They have hit the fourth most home runs as well. On the road, the Cubs have a .244 batting average and are hitting .295 in seven games against the Cardinals.

5
MLB · Chicago Cubs at St. Louis Cardinals

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St. Louis Cardinals

The St. Louis Cardinals currently have a 58-58 overall record this season, with a 32-24 record when playing at home. They are 13 games back of the Brewers for first place in the division and 5.5 games back of the Mets for the final wild card spot in the National League. The team has lost seven of their last 11 games. In their last game, the Cardinals defeated the Dodgers 5-3 on August 6th. Michael McGreevy will start for the Cardinals on August 8th, with a 3-2 record and a 5.08 ERA in six starts and one relief appearance. The Cardinals are hitting .249 this season, ranking 14th in the league in hits and runs hit. They rank eighth worst in home runs hit and have a .256 batting average during home games. However, their batting average has dropped to .236 since the All-Star break and they have a .224 batting average in seven games against the Cubs.

Cubs' Success in Friday's Game Hinges on Pitcher Matthew Boyd's Performance

The success of the Cubs in Friday's game will heavily rely on the performance of starting pitcher Matthew Boyd. Throughout the season, Boyd has consistently demonstrated his pitching prowess with an impressive 2.97 ERA in 11 road starts and a 2.34 ERA in a total of 22 starts. The Cubs significantly benefit from Boyd's strong arm on the mound and their robust hitting capabilities. Their batting average of .295 in seven games against the Cardinals showcases their offensive strength. Additionally, holding the best record in the National League wild card race further solidifies their position as a formidable opponent. Conversely, the Cardinals may face challenges in scoring runs against Boyd given their .224 batting average against Chicago and recent track record of seven losses in their last 11 games. Therefore, it is advisable to choose the Cubs as the favorable pick for this matchup.

SportsJawGame Predictions
Predicted score

Unavailable for this preview

Projected winnerUnavailableConfidencelow
Pick on the Spread

Published pick: Unavailable

Pick on the Total

Published pick: Unavailable

#ChicagoCubs#StLouisCardinals

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Written by

SportsJaw Editorial Team

SportsJaw published this archived preview from its original game-day article. Its prediction and quoted lines are preserved as written.

About our editorial process

SportsJaw Cubs vs Cardinals archived game preview contains historical odds and availability that may no longer be current. View history of past Cubs vs Cardinals matchups or learn how our predictions work.

Current matchup data

Lines, trends and availability

Line movement since open

  • Moneyline · Chicago Cubs-148 → -165Moved
  • Moneyline · St. Louis Cardinals+131 → +145Moved
  • Spread · Chicago Cubs-1.5 (+102) → -1.5 (+100)Moved
  • Spread · St. Louis Cardinals+1.5 (-122) → +1.5 (-120)Moved
  • Total · Over8.5 (-110) → 8.5 (-110)Unchanged
  • Total · Under8.5 (-110) → 8.5 (-110)Unchanged

ATS and O/U trends

Chicago Cubs
89-73 matchup record · 3-7-0 ATS · 4-5-1 O/U
Last 10 completed games on file
St. Louis Cardinals
77-85 matchup record · 4-6-0 ATS · 4-5-1 O/U
Last 10 completed games on file

Injuries and availability

From the published research (2025-08-09T03:47:56.066Z). Availability may have changed; review the cited sources.

No verified injury or availability note was included in the published matchup research.

Recent head-to-head

  • 2025-07-06St. Louis Cardinals 0 · Chicago Cubs 11
  • 2025-07-05St. Louis Cardinals 8 · Chicago Cubs 6
  • 2025-07-04St. Louis Cardinals 3 · Chicago Cubs 11
Final result

Matchup pick recap

St. Louis Cardinals defeated Chicago Cubs 5-0

St. Louis Cardinals defeated Chicago Cubs 5-0 on August 8, 2025, a 5-run decision in the series. St. Louis Cardinals' strongest period was the 5th inning, when it outscored its opponent 2-0. Against SportsJaw's recorded Chicago Cubs -1.5 (+100) spread, St. Louis Cardinals covered, while the 5 combined runs finished under the recorded total of 8.5.

SportsJaw editorial picks

  • Projected winnerNo published selectionUnavailable

Tipster picks

No graded public tipster picks were recorded for this matchup.