Houston Astros vs Miami Marlins Betting Picks & Predictions
On Wednesday, August 6, 2025, the Houston Astros will face off against the Miami Marlins in an interleague matchup at loanDepot Park in Miami, Florida. The Astros are favored
Game outlook
On Wednesday, August 6, 2025, the Houston Astros will face off against the Miami Marlins in an interleague matchup at loanDepot Park in Miami, Florida. The Astros are favored in this game with a total of 8.0 runs. The two teams are wrapping up their three-game series, with the Astros coming out on top 8-2 in the first game. Check out our Astros vs. Marlins prediction and the latest odds update for this exciting matchup. Stay tuned for more MLB picks for Wednesday's slate. The game is set to start at 4:40 PM ET.
Betting Odds
Moneyline: Astros +103 | Marlins -114
Spread: Astros +1.5 (-207) | Marlins -1.5 (+175)
Total: Over/Under 8 (-110)
Based on the moneyline, the implied probability that Miami will win straight-up is 53%.
Houston Astros
Last Monday, the Houston Astros, who were +110 underdogs, secured a victory over the Marlins thanks to Jason Alexander's strong pitching performance and Yainer Diaz's offensive contributions. The Astros went 6-for-12 with runners in scoring position, snapping a three-game losing streak. However, the team has been struggling overall, winning just three of their last 11 games. The offense has scored 37 runs with a .235/.295/.348 slash line, while the bullpen has a 4.03 ERA and 1.37 WHIP. Spencer Arrighetti will be activated from the 60-day IL to start Wednesday against the Marlins after recovering from a thumb injury. Arrighetti, with a 4.60 ERA and 1.38 WHIP in his career, has never faced the Marlins before.

