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  1. Home
  2. MLB Picks
  3. San Diego Padres vs Arizona Diamondbacks
Tue 9:40 PM ET
San Diego Padres logo
San Diego
Padres10
Y. Darvish RHP
versus
Arizona Diamondbacks logo
Arizona
Diamondbacks5
R. Nelson RHP
Final/11
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Arizona Diamondbacks2

San Diego Padres vs Arizona Diamondbacks Betting Picks & Predictions

Game time: August 5, 2025 at 9:40 PM ET

Venue: Chase Field — Phoenix, Arizona

Article updated Aug 5, 11:15 PM EDT

Published by SportsJaw Editorial Team

On August 5, the San Diego Padres will face off against the Arizona Diamondbacks in a crucial National League West division matchup. The Padres are currently in second place

Game outlook

On August 5, the San Diego Padres will face off against the Arizona Diamondbacks in a crucial National League West division matchup. The Padres are currently in second place in the NL West, just behind the Dodgers, and hold the final wild card spot. The Diamondbacks have struggled at home this season with a sub-.500 record. Ryne Nelson is set to start for Arizona, while Yu Darvish will take the mound for San Diego. The game is scheduled to begin at 9:40 P.M. EST.

Betting Odds

Moneyline: Padres -131 | Diamondbacks +115

Spread: Padres -1.5 (+119) | Diamondbacks +1.5 (-140)

Total: Over/Under 9 (-110)

Based on the moneyline, the implied probability that San Diego will win straight-up is 57%.

San Diego Padres

The San Diego Padres are currently 91-71 overall this season, holding the second place spot in the National League West division. They are also in the final wild card spot in the National League, three games ahead of the Reds for the playoff spot. The Padres have a 26-32 road record and have won seven of their last nine games. In their last game, they lost 6-2 to the Diamondbacks on August 4th. Yu Darvish will start for the Padres in the upcoming game against the Diamondbacks, with a 1-3 record and 6.46 ERA in five starts this year. In his last start against the Mets, Darvish pitched seven innings, allowing zero runs and striking out seven batters in a 5-0 win. The Padres are 2-3 in games where Darvish has started this season. San Diego has a .251 team batting average this season, ranking 12th in the league, with rankings of 7th worst in runs scored and 16th in hits. They have struck out the third fewest times this year. On the road, they have a .248 batting average and against National League West clubs, they have a .274 batting average. Specifically against Arizona, they have a .252 batting average.

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MLB · San Diego Padres at Arizona Diamondbacks

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Arizona Diamondbacks

The Arizona Diamondbacks are currently 54-59 overall this season and are in fourth place in the National League West. They are 11 games behind the first-place Dodgers. The team has a 27-28 record when playing at home and have lost nine of their last 13 games. However, they have won three straight, including a recent 6-2 victory over San Diego on Monday, August 4. Ryne Nelson will be starting against the Padres on Tuesday. Nelson, a right-handed pitcher, has a record of 6-3 with a 3.20 ERA in 13 starts and 10 relief appearances. The Diamondbacks have an 8-5 record in games started by Nelson. The team has a batting average of .249 this season, ranking 14th, and has scored the seventh most runs in the league. They also rank sixth in home runs hit. However, against San Diego, they are hitting .213.

San Diego Padres Brace for Tough Road Test Against Arizona Diamondbacks

The San Diego Padres have demonstrated a strong performance this year, currently holding a wild card spot in the National League. Despite being within striking distance of the divisional lead, their upcoming matchup on Tuesday may prove challenging, as Yu Darvish has struggled on the road this season. With a high road ERA and the Arizona Diamondbacks' solid home batting average, the Padres are facing a formidable opponent in this game. Relying on starting pitcher Ryne Nelson, who boasts an impressive home ERA and a winning record when pitching at home, the Diamondbacks are well positioned for success in this game. With these factors in mind, it is advisable to favor Arizona in this low-scoring matchup.

SportsJawGame Predictions
Predicted score

Unavailable for this preview

Projected winnerUnavailableConfidencelow
Pick on the Spread

Published pick: Unavailable

Pick on the Total

Published pick: Unavailable

#SanDiegoPadres#ArizonaDiamondbacks

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Written by

SportsJaw Editorial Team

SportsJaw published this archived preview from its original game-day article. Its prediction and quoted lines are preserved as written.

About our editorial process

SportsJaw Padres vs Diamondbacks archived game preview contains historical odds and availability that may no longer be current. View history of past Padres vs Diamondbacks matchups or learn how our predictions work.

Current matchup data

Lines, trends and availability

Line movement since open

  • Moneyline · San Diego Padres-136 → -118Moved
  • Moneyline · Arizona Diamondbacks+118 → +104Moved
  • Spread · San Diego Padres-1.5 (+120) → -1.5 (+135)Moved
  • Spread · Arizona Diamondbacks+1.5 (-140) → +1.5 (-155)Moved
  • Total · Over9 (-110) → 9 (-110)Unchanged
  • Total · Under9 (-110) → 9 (-110)Unchanged

ATS and O/U trends

San Diego Padres
91-71 matchup record · 6-4-0 ATS · 4-6-0 O/U
Last 10 completed games on file
Arizona Diamondbacks
86-76 matchup record · 3-7-0 ATS · 1-7-2 O/U
Last 10 completed games on file

Injuries and availability

From the published research (2025-08-06T03:15:11.911Z). Availability may have changed; review the cited sources.

No verified injury or availability note was included in the published matchup research.

Recent head-to-head

  • 2025-08-04San Diego Padres 2 · Arizona Diamondbacks 6
  • 2025-07-10Arizona Diamondbacks 3 · San Diego Padres 4
  • 2025-07-09Arizona Diamondbacks 8 · San Diego Padres 2
  • 2025-07-08Arizona Diamondbacks 0 · San Diego Padres 1
  • 2025-07-07Arizona Diamondbacks 6 · San Diego Padres 3
Final result

Matchup pick recap

San Diego Padres defeated Arizona Diamondbacks 10-5

San Diego Padres defeated Arizona Diamondbacks 10-5 on August 5, 2025, a 5-run decision in the series. San Diego Padres' strongest period was the 11th inning, when it outscored its opponent 5-0. Against SportsJaw's recorded San Diego Padres -1.5 (+135) spread, San Diego Padres covered, while the 15 combined runs finished over the recorded total of 9.

SportsJaw editorial picks

  • Projected winnerNo published selectionUnavailable

Tipster picks

No graded public tipster picks were recorded for this matchup.