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  1. Home
  2. MLB Picks
  3. Chicago Cubs vs Los Angeles Angels
Sat 9:38 PM ET
Chicago Cubs logo
Chicago
Cubs12
C. Horton RHP
versus
Los Angeles Angels logo
Los Angeles
Angels1
V. Mederos RHP
Final
Team123456789T
Chicago Cubs00240420012
Los Angeles Angels000000100

Chicago Cubs vs Los Angeles Angels Betting Picks & Predictions

Game time: August 23, 2025 at 9:38 PM ET

Venue: Angel Stadium — Anaheim, California

Article updated Aug 23, 8:15 PM EDT

Published by SportsJaw Editorial Team

The 2025 Major League Baseball season kicks off on Saturday, August 23, with the Chicago Cubs facing off against the Los Angeles Angels at Angel Stadium in Anaheim, CA. This

Game outlook

The 2025 Major League Baseball season kicks off on Saturday, August 23, with the Chicago Cubs facing off against the Los Angeles Angels at Angel Stadium in Anaheim, CA. This interleague matchup is part of a three-game series between the two teams, with Friday night's game not factoring into the analysis. Our Cubs vs. Angels prediction provides insight on what to expect from this exciting showdown. Be sure to stay tuned for more MLB picks for Saturday's slate of games. The first pitch at Angel Stadium is scheduled for 9:38 PM ET.

Betting Odds

Moneyline: Cubs -145 | Angels +131

Spread: Cubs -1.5 (+105) | Angels +1.5 (-124)

Total: Over/Under 10 (-110)

Based on the moneyline, the implied probability that Chicago will win straight-up is 59%.

Chicago Cubs

The Chicago Cubs had a successful five-game series against the Milwaukee Brewers, winning three out of five games. However, their starting rotation faced challenges after a doubleheader on Tuesday. It is uncertain who will start the opening game of the upcoming series. Cade Horton, who was expected to pitch on Saturday, may miss his turn due to a blister on his finger. Despite this setback, Horton has been performing well recently. The Cubs are currently leading the wild card race in the National League. Their offense has struggled in the last week, with a low batting average and few home runs. On the other hand, their bullpen has been performing decently with a 3.68 ERA.

1
MLB · Chicago Cubs at Los Angeles Angels

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Los Angeles Angels

The Los Angeles Angels recently dropped a three-game home series against the Cincinnati Reds, with a 4-1 defeat in the opener, a 6-4 loss in the middle game, and a 2-1 win in the closer to avoid a sweep. The Angels' starting rotation is facing some challenges, with Jose Soriano on paternity leave and Tyler Anderson dealing with a back injury. It is uncertain who will start on Saturday night, and the team may consider a bullpen day or turn to Victor Mederos, who has struggled with a 0-1 record, a 5.54 ERA, and a 1.85 WHIP in 2025. The Angels are currently 6.5 games behind the bottom wildcard spot in the American League, with a .237/.326/.385 slash line and five home runs in the last seven days. Their bullpen has posted a 5.06 ERA, a 1.50 WHIP, and a .268 batting average against during that time.

Chicago Cubs Have the Edge in Pitching and Offense Leading Up to Game Against Los Angeles Angels

There are several factors to consider in the upcoming game between Chicago and Los Angeles. Both teams may choose to utilize a bullpen day, with Chicago appearing to have a deeper pitching rotation than Los Angeles. Despite recent struggles at the plate, the Cubs have shown strong offensive capabilities throughout the season thus far. Chicago currently ranks fifth in the league for runs scored per game, while Los Angeles ranks 16th in the same category. It is advised to stay updated on any developments leading up to the game. If Cade Horton is chosen to pitch, it is recommended to select the Cubs without hesitation. Even in the event of a bullpen day or if Victor Mederos starts for the Angels, I would still favor the Cubs in this matchup.

SportsJawGame Predictions
Predicted score

Unavailable for this preview

Projected winnerUnavailableConfidencelow
Pick on the Spread

Published pick: Unavailable

Pick on the Total

Published pick: Unavailable

#ChicagoCubs#LosAngelesAngels

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Written by

SportsJaw Editorial Team

SportsJaw published this archived preview from its original game-day article. Its prediction and quoted lines are preserved as written.

About our editorial process

SportsJaw Cubs vs Angels archived game preview contains historical odds and availability that may no longer be current. View history of past Cubs vs Angels matchups or learn how our predictions work.

Current matchup data

Lines, trends and availability

Line movement since open

  • Moneyline · Chicago Cubs-145 → -147Moved
  • Moneyline · Los Angeles Angels+127 → +130Moved
  • Spread · Chicago Cubs-1.5 (+105) → -1.5 (+104)Moved
  • Spread · Los Angeles Angels+1.5 (-125) → +1.5 (-122)Moved
  • Total · Over9.5 (-110) → 9.5 (-110)Unchanged
  • Total · Under9.5 (-110) → 9.5 (-110)Unchanged

ATS and O/U trends

Chicago Cubs
89-73 matchup record · 4-6-0 ATS · 2-7-1 O/U
Last 10 completed games on file
Los Angeles Angels
62-100 matchup record · 5-5-0 ATS · 6-4-0 O/U
Last 10 completed games on file

Injuries and availability

From the published research (2025-08-24T00:15:35.631Z). Availability may have changed; review the cited sources.

The Los Angeles Angels recently dropped a three-game home series against the Cincinnati Reds, with a 4-1 defeat in the opener, a 6-4 loss in the middle game, and a 2-1 win in the closer to avoid a sweep. The Angels' starting rotation is facing some challenges, with Jose Soriano on paternity leave and Tyler Anderson dealing with a back injury. It is uncertain who will start on Saturday night, and the team may consider a bullpen day or turn to Victor Mederos, who has struggled with a 0-1 record, a 5.54 ERA, and a 1.85 WHIP in 2025. The Angels are currently 6.5 games behind the bottom wildcard spot in the American League, with a .237/.326/.385 slash line and five home runs in the last seven days. Their bullpen has posted a 5.06 ERA, a 1.50 WHIP, and a .268 batting average against during that time.

Recent head-to-head

  • 2025-08-22Chicago Cubs 3 · Los Angeles Angels 2
Final result

Matchup pick recap

Chicago Cubs defeated Los Angeles Angels 12-1

Chicago Cubs defeated Los Angeles Angels 12-1 on August 23, 2025, a 11-run decision in the series. Chicago Cubs' strongest period was the 4th inning, when it outscored its opponent 4-0. Against SportsJaw's recorded Chicago Cubs -1.5 (+104) spread, Chicago Cubs covered, while the 13 combined runs finished over the recorded total of 9.5.

SportsJaw editorial picks

  • Projected winnerNo published selectionUnavailable

Tipster picks

No graded public tipster picks were recorded for this matchup.