Chicago Cubs vs Los Angeles Angels Betting Picks & Predictions
The 2025 Major League Baseball season kicks off on Saturday, August 23, with the Chicago Cubs facing off against the Los Angeles Angels at Angel Stadium in Anaheim, CA. This
Game outlook
The 2025 Major League Baseball season kicks off on Saturday, August 23, with the Chicago Cubs facing off against the Los Angeles Angels at Angel Stadium in Anaheim, CA. This interleague matchup is part of a three-game series between the two teams, with Friday night's game not factoring into the analysis. Our Cubs vs. Angels prediction provides insight on what to expect from this exciting showdown. Be sure to stay tuned for more MLB picks for Saturday's slate of games. The first pitch at Angel Stadium is scheduled for 9:38 PM ET.
Betting Odds
Moneyline: Cubs -145 | Angels +131
Spread: Cubs -1.5 (+105) | Angels +1.5 (-124)
Total: Over/Under 10 (-110)
Based on the moneyline, the implied probability that Chicago will win straight-up is 59%.
Chicago Cubs
The Chicago Cubs had a successful five-game series against the Milwaukee Brewers, winning three out of five games. However, their starting rotation faced challenges after a doubleheader on Tuesday. It is uncertain who will start the opening game of the upcoming series. Cade Horton, who was expected to pitch on Saturday, may miss his turn due to a blister on his finger. Despite this setback, Horton has been performing well recently. The Cubs are currently leading the wild card race in the National League. Their offense has struggled in the last week, with a low batting average and few home runs. On the other hand, their bullpen has been performing decently with a 3.68 ERA.

