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  1. Home
  2. MLB Picks
  3. Minnesota Twins vs Chicago White Sox
Fri 7:40 PM ET
Minnesota Twins logo
Minnesota
Twins9
Z. Matthews RHP
versus
Chicago White Sox logo
Chicago
White Sox7
A. Civale RHP
Final
Team123456789T
Minnesota Twins0004022019
Chicago White Sox10012003

Minnesota Twins vs Chicago White Sox Betting Picks & Predictions

Game time: August 22, 2025 at 7:40 PM ET

Venue: Rate Field — Chicago, Illinois

Article updated Aug 22, 8:14 AM EDT

Published by SportsJaw Editorial Team

The Minnesota Twins and Chicago White Sox are set to face off in a three-game series starting Friday night at Guaranteed Rate Field. The Twins hold a 4-2 advantage over the

Game outlook

The Minnesota Twins and Chicago White Sox are set to face off in a three-game series starting Friday night at Guaranteed Rate Field. The Twins hold a 4-2 advantage over the White Sox in their head-to-head matchups this season. Both teams are looking to snap losing streaks coming into this series. Stay tuned for our prediction on the outcome of this game.

Betting Odds

Moneyline: Twins -137 | White Sox +122

Spread: Twins -1.5 (+125) | White Sox +1.5 (-145)

Total: Over/Under 8.5 (-110)

Based on the moneyline, the implied probability that Minnesota will win straight-up is 58%.

Minnesota Twins

Despite recent struggles, the Minnesota Twins hold an edge on paper going into their matchup. The team has shown solid offensive power, led by Byron Buxton, Trevor Larnach, and Brooks Lee. While their team batting average and run production are modest, they have hit 136 home runs this season. On the mound, Zebby Matthews will look to stabilize a pitching staff that ranks 15th in MLB with a 4.26 ERA. The bullpen has 22 saves but has struggled overall with a 4.24 ERA and low strikeout numbers.

Chicago White Sox

The Chicago White Sox have been struggling recently, losing six of their last seven games, including a 1-0 loss to the Atlanta Braves. The team's offense has been problematic all season, ranking near the bottom in scoring, batting average, and home runs. Despite this, Lenyn Sosa has been a standout with a .271 average, 17 home runs, and 55 RBI. Aaron Civale will start on Friday with a 3-8 record and a 4.88 ERA. He has had mixed results since joining Chicago, but has a history of struggling against the Twins. The team's bullpen is ranked 17th with a 3.98 ERA.

0
7
MLB · Minnesota Twins at Chicago White Sox

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21+. Gambling problem? Call 1-800-GAMBLER. Picks are opinions, not guarantees. Past results do not predict future outcomes.

Twins to Start Matthews Against White Sox: White Sox the Underdog in Matchup

Zebby Matthews, recently activated from a 15-day stint on the injured list, will be starting for the Twins. Matthews, with a record of 2-3 and a 5.46 ERA on the road this season, has struggled in his recent outings, resulting in three losses out of his last four starts. Aaron Civale, on the other hand, has shown consistency in four out of his last five appearances despite a rough outing against Cleveland on August 8. Both teams have been facing challenges in securing wins recently, but the White Sox demonstrated resilience in a recent game against Atlanta. Considering these factors, I am inclined to support the White Sox as an underdog in this matchup.

SportsJawGame Predictions
Predicted score

Unavailable for this preview

Projected winnerUnavailableConfidencelow
Pick on the Spread

Published pick: Unavailable

Pick on the Total

Published pick: Unavailable

#MinnesotaTwins#ChicagoWhiteSox

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Written by

SportsJaw Editorial Team

SportsJaw published this archived preview from its original game-day article. Its prediction and quoted lines are preserved as written.

About our editorial process

SportsJaw Twins vs White Sox archived game preview contains historical odds and availability that may no longer be current. View history of past Twins vs White Sox matchups or learn how our predictions work.

Current matchup data

Lines, trends and availability

Line movement since open

  • Moneyline · Minnesota Twins-139 → -130Moved
  • Moneyline · Chicago White Sox+122 → +110Moved
  • Spread · Minnesota Twins-1.5 (+125) → -1.5 (+129)Moved
  • Spread · Chicago White Sox+1.5 (-145) → +1.5 (-150)Moved
  • Total · Over8.5 (-110) → 8.5 (-110)Unchanged
  • Total · Under8.5 (-110) → 8.5 (-110)Unchanged

ATS and O/U trends

Minnesota Twins
77-85 matchup record · 3-7-0 ATS · 4-5-1 O/U
Last 10 completed games on file
Chicago White Sox
84-78 matchup record · 7-3-0 ATS · 4-6-0 O/U
Last 10 completed games on file

Injuries and availability

From the published research (2025-08-22T12:14:15.853Z). Availability may have changed; review the cited sources.

Zebby Matthews, recently activated from a 15-day stint on the injured list, will be starting for the Twins. Matthews, with a record of 2-3 and a 5.46 ERA on the road this season, has struggled in his recent outings, resulting in three losses out of his last four starts. Aaron Civale, on the other hand, has shown consistency in four out of his last five appearances despite a rough outing against Cleveland on August 8. Both teams have been facing challenges in securing wins recently, but the White Sox demonstrated resilience in a recent game against Atlanta. Considering these factors, I am inclined to support the White Sox as an underdog in this matchup.

Recent head-to-head

No completed head-to-head result is available in the current history window.

Final result

Matchup pick recap

Minnesota Twins defeated Chicago White Sox 9-7

Minnesota Twins defeated Chicago White Sox 9-7 on August 22, 2025, a 2-run decision in the series. Minnesota Twins' strongest period was the 4th inning, when it outscored its opponent 4-1. Against SportsJaw's recorded Minnesota Twins -1.5 (+129) spread, Minnesota Twins covered, while the 16 combined runs finished over the recorded total of 8.5.

SportsJaw editorial picks

  • Projected winnerNo published selectionUnavailable

Tipster picks

  • 1188460207Moneyline · Chicago White Sox +122Loss
  • HitmanhartMoneyline · Chicago White Sox +122Loss
  • Fisher49Moneyline · Minnesota Twins -137Win
  • RcollinsMoneyline · Chicago White Sox +122Loss
  • JohnnywalkerMoneyline · Chicago White Sox +122Loss
  • JohnnywalkerTotal · Over 8.5 (-110)Win
  • JtphamMoneyline · Minnesota Twins -137Win
  • NutinbutlocksMoneyline · Chicago White Sox +122Loss
  • Hustle$Total · Under 8.5 (-110)Loss
  • DtownsendMoneyline · Minnesota Twins -129Win
  • PremierPicksMoneyline · Chicago White Sox +116Loss
  • IroncladlocksMoneyline · Minnesota Twins -129Win
  • BillywatersMoneyline · Chicago White Sox +116Loss
  • Josh720Moneyline · Chicago White Sox +116Loss