San Francisco Giants vs
San Diego PadresPredictions & Preview

Giants Face Tough Challenge Against Padres in Game Three of Series

The San Francisco Giants are set to play game three of a four-game series against the San Diego Padres at Petco Park. The Giants defeated the Padres in the opening game of the series and have won two straight after a seven-game losing streak. San Francisco is currently 10 games behind first place in the NL West and 5.5 games behind the third NL wildcard spot. The Padres have lost four straight and are two games behind first-place Los Angeles in the NL West. Both teams will be missing several key players in the upcoming matchup. For a more in-depth analysis and prediction of the game, be sure to check out our MLB picks for the San Francisco Giants vs. San Diego Padres matchup.

Betting Odds

• Moneyline: Giants +125 | Padres -138
• Spread: Giants +1.5 (-185) | Padres -1.5 (+151)
• Total: Over/Under 8 (-110)
• Based on the moneyline, the implied probability that San Diego will win straight-up is 58%.

San Francisco Giants

The San Francisco Giants currently rank 21st in on-base percentage and 25th in both runs scored and batting average in the league. Willy Adames leads the team in home runs and Wilmer Flores leads in RBI. The Giants have strong pitching stats, ranking 5th in ERA and 7th in Quality Starts. Logan Webb leads the team in wins and strikeouts, while Robbie Ray has the best ERA among starters. Landen Roupp will be starting for the Giants on Wednesday with a 7-6 record and a 3.45 ERA this season.

San Diego Padres

The San Diego Padres have been performing well in multiple areas this season. Offensively, they are ranked 8th in on-base percentage, 9th in batting average, and have scored 518 runs. Manny Machado has been a standout player, leading the team in doubles, home runs, and RBI. Fernando Tatus Jr and Gavin Sheets have also been key contributors. The Padres have a total of 312 extra base hits, including 200 doubles. On the pitching side, the team is excelling with a low batting average against, a strong ERA, and WHIP. Nick Pivetta leads in wins and ERA, while Dylan Cease leads in strikeouts. As of now, the starting pitcher for Wednesday's game against San Francisco has not been released.

San Francisco Giants Struggle Against Dominant San Diego Padres

The San Francisco Giants have faced a challenging stretch recently, losing seven of their last nine games. In head-to-head matchups against the San Diego Padres, the Giants have struggled even more, dropping 10 of the last 13 games. The Padres have been dominant against National League teams, winning 12 of their last 18 matchups. San Diego's pitching staff has been particularly strong, ranking third in both ERA and WHIP. They also lead the league in batting average against at .226. Additionally, the Padres boast the best bullpen ERA in baseball at 2.95, while the Giants are close behind at 3.29. Giants starter Landen Roupp has had a tough time against the Padres this season, suffering losses in both of his outings. In a total of 10.2 innings pitched against San Diego, Roupp has allowed four earned runs, resulting in an ERA of 3.53.

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