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  1. Home
  2. MLB Picks
  3. St. Louis Cardinals vs San Diego Padres
Sat 10:10 PM ET
St. Louis Cardinals logo
St. Louis
Cardinals8
M. McGreevy RHP
versus
San Diego Padres logo
San Diego
Padres5
R. Vasquez RHP
Final
Team123456789T
St. Louis Cardinals0004200028
San Diego Padres1210000

St. Louis Cardinals vs San Diego Padres Betting Picks & Predictions

Game time: August 2, 2025 at 10:10 PM ET

Venue: Petco Park — San Diego, California

Article updated Aug 2, 7:15 PM EDT

Published by SportsJaw Editorial Team

This Saturday, the St. Louis Cardinals and the San Diego Padres will face off at Petco Park after recently splitting a four-game series in St. Louis. The Padres are currently

Game outlook

This Saturday, the St. Louis Cardinals and the San Diego Padres will face off at Petco Park after recently splitting a four-game series in St. Louis. The Padres are currently in a postseason position, while the Cardinals are fading from the race. Both teams are experiencing different emotions following the recent trade deadline.

Betting Odds

Moneyline: Cardinals +128 | Padres -145

Spread: Cardinals +1.5 (-166) | Padres -1.5 (+145)

Total: Over/Under 8.5 (-110)

Based on the moneyline, the implied probability that San Diego will win straight-up is 59%.

St. Louis Cardinals

The St. Louis Cardinals currently hold a 55-55 record and are struggling in the standings, sitting 10 games behind in the National League Central and 5.5 games out of a wild card spot. All-Star third baseman Nolan Arenado has been placed on the 10-day injured list due to a shoulder issue, leaving the team without one of their top run producers for at least a week. Offensively, the Cards have shown potential with Alec Burleson leading the way in batting average and Willson Contreras providing power with 14 home runs. On the mound, Michael McGreevy will start, despite his inconsistency, and the team's defense is average with a 4.17 ERA and 1.28 WHIP. With the season hanging by a thread and Arenado sidelined, the Cardinals' chances of making the playoffs are looking increasingly slim.

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MLB · St. Louis Cardinals at San Diego Padres

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San Diego Padres

The San Diego Padres are currently in a strong position in the NL West and wild card race, just two games behind the Dodgers. The team's front office made strategic moves at the trade deadline to boost their chances of reaching October baseball. With a solid home record and strong pitching staff led by Randy Vasquez, the Padres are in a good position. Offensively, Manny Machado and Luis Arraez have been key contributors, while Fernando Tatis Jr. brings power and speed. The team's offense has been steady and timely, and their strong defense has helped them maintain a top-ranked team ERA. With a healthy and motivated roster, the Padres are poised for a successful playoff push.

San Diego Padres poised for victory in upcoming matchup against St. Louis Cardinals

The San Diego Padres appear to have a significant advantage in the upcoming matchup. The team has more incentive to win, as well as better recent performance and stronger pitching. Randy Vasquez, the Padres' starting pitcher, has had a string of successful outings, winning six consecutive games, including a recent victory over the St. Louis Cardinals. His consistency and effectiveness at home make him a reliable choice for the Padres. On the other hand, Cardinals starter Gordon Graceffo McGreevy has struggled in his previous game against San Diego and is still acclimating to the challenges of Major League Baseball. Furthermore, the absence of Nolan Arenado weakens the Cardinals' offense, which has already shown inconsistencies. Even in the event of a battle between bullpens, the Padres have the upper hand with the best bullpen ERA in MLB. Considering all these factors, it is likely that the Padres will emerge victorious once again.

SportsJawGame Predictions
Predicted score

Unavailable for this preview

Projected winnerUnavailableConfidencelow
Pick on the Spread

Published pick: Unavailable

Pick on the Total

Published pick: Unavailable

#StLouisCardinals#SanDiegoPadres

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Written by

SportsJaw Editorial Team

SportsJaw published this archived preview from its original game-day article. Its prediction and quoted lines are preserved as written.

About our editorial process

SportsJaw Cardinals vs Padres archived game preview contains historical odds and availability that may no longer be current. View history of past Cardinals vs Padres matchups or learn how our predictions work.

Current matchup data

Lines, trends and availability

Line movement since open

  • Moneyline · St. Louis Cardinals+122 → +127Moved
  • Moneyline · San Diego Padres-137 → -147Moved
  • Spread · St. Louis Cardinals+1.5 (-175) → +1.5 (-165)Moved
  • Spread · San Diego Padres-1.5 (+153) → -1.5 (+140)Moved
  • Total · Over8.5 (-110) → 8.5 (-110)Unchanged
  • Total · Under8.5 (-110) → 8.5 (-110)Unchanged

ATS and O/U trends

St. Louis Cardinals
77-85 matchup record · 3-7-0 ATS · 2-6-2 O/U
Last 10 completed games on file
San Diego Padres
91-71 matchup record · 6-4-0 ATS · 3-7-0 O/U
Last 10 completed games on file

Injuries and availability

From the published research (2025-08-02T23:15:30.647Z). Availability may have changed; review the cited sources.

The St. Louis Cardinals currently hold a 55-55 record and are struggling in the standings, sitting 10 games behind in the National League Central and 5.5 games out of a wild card spot. All-Star third baseman Nolan Arenado has been placed on the 10-day injured list due to a shoulder issue, leaving the team without one of their top run producers for at least a week. Offensively, the Cards have shown potential with Alec Burleson leading the way in batting average and Willson Contreras providing power with 14 home runs. On the mound, Michael McGreevy will start, despite his inconsistency, and the team's defense is average with a 4.17 ERA and 1.28 WHIP. With the season hanging by a thread and Arenado sidelined, the Cardinals' chances of making the playoffs are looking increasingly slim.

Recent head-to-head

  • 2025-08-01St. Louis Cardinals 1 · San Diego Padres 4
  • 2025-07-27San Diego Padres 9 · St. Louis Cardinals 2
  • 2025-07-26San Diego Padres 3 · St. Louis Cardinals 1
  • 2025-07-25San Diego Padres 0 · St. Louis Cardinals 3
  • 2025-07-24San Diego Padres 7 · St. Louis Cardinals 9
Final result

Matchup pick recap

St. Louis Cardinals defeated San Diego Padres 8-5

St. Louis Cardinals defeated San Diego Padres 8-5 on August 2, 2025, a 3-run decision in the series. St. Louis Cardinals' strongest period was the 4th inning, when it outscored its opponent 4-0. Against SportsJaw's recorded St. Louis Cardinals +1.5 (-165) spread, St. Louis Cardinals covered, while the 13 combined runs finished over the recorded total of 8.5.

SportsJaw editorial picks

  • Projected winnerNo published selectionUnavailable

Tipster picks

No graded public tipster picks were recorded for this matchup.