New York Yankees vs
St. Louis CardinalsPredictions & Preview

St. Louis Cardinals Favored Over New York Yankees in Upcoming Interleague Showdown: Latest Odds and Prediction

The 2025 MLB season will feature a matchup between the New York Yankees and the St. Louis Cardinals on Saturday, August 16 at Busch Stadium in St. Louis, Missouri. This interleague showdown is part of a three-game regular-season series between the two teams. In this article, we provide a prediction for the Yankees vs. Cardinals game and the latest odds update. The Yankees are currently favored with a moneyline of -160 and a total of 8.0 runs. The game is scheduled to start at 7:15 PM ET. Be sure to stay tuned for more MLB picks for Saturday's slate. Please note that this article was written before Friday's results.

Betting Odds

• Moneyline: Yankees -142 | Cardinals +129
• Spread: Yankees -1.5 (+108) | Cardinals +1.5 (-128)
• Total: Over/Under 8 (-110)
• Based on the moneyline, the implied probability that New York will win straight-up is 59%.

New York Yankees

The New York Yankees have faced challenges recently, winning only three of their last eight series. Despite dropping series against the Texas Rangers and Houston Astros, they managed to win two out of three games against the Minnesota Twins. As of Friday, they are 6.5 games behind the AL East-leading Toronto Blue Jays and hold the bottom wild card spot in the American League. In August, the Yankees have struggled with a .215 batting average and their bullpen has a 4.70 ERA. Max Fried will pitch on Saturday night, holding a 12-5 record with a 2.94 ERA this season. While he has struggled recently, he has had success against the St. Louis Cardinals in his career.

St. Louis Cardinals

The St. Louis Cardinals have had a mixed performance in their last three series, winning against the Los Angeles Dodgers and Chicago Cubs but losing to the Colorado Rockies. They are currently behind in the playoff race but hope for a strong push in the coming days. In August, their hitting and bullpen have been inconsistent. However, Sonny Gray will be pitching on Saturday night with a solid record and recent improvement in performance. He has had success against the Yankees in the past. Fans are hopeful for a positive outcome in the upcoming game.

St. Louis Cardinals Favored Over New York Yankees in Upcoming Matchup Due to Struggles in Lineup and Bullpen

Currently, the New York Yankees are experiencing challenges with their struggling lineup and underperforming bullpen. Max Fried's recent performance also raises concerns, as he has allowed a minimum of four runs in his last five starts. Taking these factors into consideration, the St. Louis Cardinals appear to be a more favorable option, especially given their strong offensive performance against left-handed pitchers. Sonny Gray, who has displayed excellent pitching in his last two starts, is expected to deliver another impressive performance when facing the Yankees. This analysis suggests that the Cardinals, with promising odds, are the recommended choice for the upcoming matchup.

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