Washington Nationals vs Minnesota Twins Betting Picks & Predictions
The Washington Nationals will face off against the Minnesota Twins in an interleague showdown at Target Field on Friday, July 25, 2025. The Twins are currently favored with a
Game outlook
The Washington Nationals will face off against the Minnesota Twins in an interleague showdown at Target Field on Friday, July 25, 2025. The Twins are currently favored with a -159 moneyline and a total of 8.5 runs. Last year, the Twins won two out of three games against the Nationals. The first pitch is scheduled for 8:10 PM ET. Stay tuned for our Nationals vs. Twins prediction and the latest odds update.
Betting Odds
Moneyline: Nationals +143 | Twins -158
Spread: Nationals +1.5 (-168) | Twins -1.5 (+148)
Total: Over/Under 8.5 (-110)
Based on the moneyline, the implied probability that Minnesota will win straight-up is 61%.
Washington Nationals
The Washington Nationals recently suffered a 5-0 loss to the Cincinnati Reds, missing the opportunity to sweep after winning the first two games of a three-game series. Since the All-Star break, the Nationals have gone 3-3 and are currently last in the NL East, 14 games behind the bottom wild-card spot. MacKenzie Gore is slated to start on Friday night at Target Field with a 4-9 record, 3.59 ERA, and 1.27 WHIP in 20 starts this season. In his last outing, Gore struggled, allowing eight earned runs in just 2.1 innings. He will face the Minnesota Twins for the first time, with only three players from the Twins having prior experience facing him.
Minnesota Twins
The Minnesota Twins have struggled in the second half of the season, going 2-4 in recent games. They recently finished a six-game road trip, experiencing losses against the Colorado Rockies and Los Angeles Dodgers. Despite scoring 32 runs in their last six games, the Twins have struggled with a 5.86 ERA and 1.46 WHIP. They are currently five games behind the final wild card spot in the American League. Zebby Matthews is set to start on Friday night, with a 1-2 record, 6.26 ERA, and 1.61 WHIP in five starts this season. In his last outing, Matthews gave up five earned runs against the Rockies. He has yet to face the Nationals and has a 77-85 record with a 6.35 ERA in interleague starts.

