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  1. Home
  2. MLB Picks
  3. St. Louis Cardinals vs Colorado Rockies
Mon 8:40 PM ET
St. Louis Cardinals logo
St. Louis
Cardinals6
M. McGreevy RHP
versus
Colorado Rockies logo
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A. Gomber LHP
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Cardinals Look to Capitalize on Matchup Against Struggling Rockies After Tough Series Against Diamondbacks

Game time: July 21, 2025 at 8:40 PM ET

Venue: Coors Field — Denver, Colorado

Article updated Jul 21, 2:14 PM EDT

Published by SportsJaw Editorial Team

The St. Louis Cardinals are regrouping after a tough series against the Diamondbacks and are preparing for a critical road game against the struggling Colorado Rockies.

Game outlook

The St. Louis Cardinals are regrouping after a tough series against the Diamondbacks and are preparing for a critical road game against the struggling Colorado Rockies. Despite their previous success, the Cardinals now sit in fourth place in the NL Central and may need to consider making changes before the trade deadline. Stay tuned for our free pick on the Cardinals vs Rockies matchup.

Betting Odds

Moneyline: Cardinals -150 | Rockies +135

Spread: Cardinals -1.5 (-105) | Rockies +1.5 (-115)

Total: Over/Under 11.5 (-110)

Based on the moneyline, the implied probability that St. Louis will win straight-up is 60%.

St. Louis Cardinals

The St. Louis Cardinals arrive in Colorado looking to bounce back from a tough series against the Arizona Diamondbacks, where vulnerabilities in their pitching and lineup were exposed. Currently standing at 51-49, they are fourth in the NL Central and 3.5 games out of a Wild Card spot. Every game is crucial with 62 games left in the season, making it essential for the Cardinals to perform well against the Rockies. Offensively, St. Louis has been solid, averaging 4.5 runs per game and holding a .251 team batting average. Defensively, they have been strong, with just 39 errors on the season. Michael McGreevy, with a 1-1 record and 4.22 ERA, will take the mound for the Cardinals in this important game.

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MLB · St. Louis Cardinals at Colorado Rockies

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Colorado Rockies

The Colorado Rockies are currently experiencing a historically difficult season in Major League Baseball. With a 24-75 overall record and 12-37 record at Coors Field, the team has struggled in all aspects of the game. Their pitching staff has the highest ERA (5.57) and worst WHIP (1.57) in the league, while their defense leads in errors with 81. Offensively, the Rockies rank poorly in runs per game, batting average, and OPS. Despite these challenges, 25-year-old catcher Hunter Goodman has stood out as a bright spot for the team. He leads in home runs, batting average, and RBI, providing some positivity in an otherwise difficult season. Monday's starter, Austin Gomber, has struggled with a 0-3 record, 5.65 ERA, and 1.60 WHIP, especially in home starts where his ERA is 7.36.

Cardinals Favored Over Rockies Following Series Sweep: Advantageous Matchup Ahead

The Cardinals are the preferred choice in this situation following a series sweep by the Diamondbacks. St. Louis is in dire need of a rebound and has an advantageous matchup ahead. Rockies pitcher Austin Gomber has struggled significantly against his former team, with a 6.67 ERA in six career appearances against the Cardinals. Colorado has yet to win any of Gomber's last five starts, contributing to their ongoing losing streak and potential placement among the worst 100-game records in modern MLB history. On the contrary, the Cardinals have a 5-1 record in Mitch McGreevy's six career starts, including a victory in Colorado last season. Based on these factors, St. Louis clearly holds the advantage in this matchup.

SportsJawGame Predictions
Predicted score

Unavailable for this preview

Projected winnerUnavailableConfidencelow
Pick on the Spread

Published pick: Unavailable

Pick on the Total

Published pick: Unavailable

#StLouisCardinals#ColoradoRockies

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Written by

SportsJaw Editorial Team

SportsJaw published this archived preview from its original game-day article. Its prediction and quoted lines are preserved as written.

About our editorial process

SportsJaw Cardinals vs Rockies archived game preview contains historical odds and availability that may no longer be current. View history of past Cardinals vs Rockies matchups or learn how our predictions work.

Current matchup data

Lines, trends and availability

Line movement since open

  • Moneyline · St. Louis Cardinals-136 → -175Moved
  • Moneyline · Colorado Rockies+115 → +151Moved
  • Spread · St. Louis Cardinals-1.5 (+108) → -1.5 (-118)Moved
  • Spread · Colorado Rockies+1.5 (-128) → +1.5 (+100)Moved
  • Total · Over11.5 (-110) → 11.5 (-110)Unchanged
  • Total · Under11.5 (-110) → 11.5 (-110)Unchanged

ATS and O/U trends

St. Louis Cardinals
51-49 matchup record · 3-7-0 ATS · 7-2-1 O/U
Last 10 completed games on file
Colorado Rockies
24-75 matchup record · 5-5-0 ATS · 4-6-0 O/U
Last 10 completed games on file

Injuries and availability

From the published research (2025-07-21T18:14:10.796Z). Availability may have changed; review the cited sources.

No verified injury or availability note was included in the published matchup research.

Recent head-to-head

No completed head-to-head result is available in the current history window.

Final result

Matchup pick recap

St. Louis Cardinals defeated Colorado Rockies 6-2

St. Louis Cardinals defeated Colorado Rockies 6-2 on July 21, 2025, a 4-run decision in the series. St. Louis Cardinals' strongest period was the 4th inning, when it outscored its opponent 2-0. Against SportsJaw's recorded St. Louis Cardinals -1.5 (-118) spread, St. Louis Cardinals covered, while the 8 combined runs finished under the recorded total of 11.5.

SportsJaw editorial picks

  • Projected winnerNo published selectionUnavailable

Tipster picks

  • BlazervegasMoneyline · St. Louis Cardinals -150Win
  • BrycetMoneyline · St. Louis Cardinals +135Win
  • DerekFisherTotal · Over 11.5 (-110)Loss
  • BooksworstnightmareMoneyline · St. Louis Cardinals -150Win