Cincinnati Reds vs
St. Louis CardinalsPredictions & Preview

NL Central Showdown: Reds at Cardinals in Pivotal Series Opener with St. Louis Favored

In this Reds at Cardinals prediction, two NL Central Division rivals will face off in a pivotal three-game series in St. Louis. Both teams are in a tight race behind the Cubs in the division standings, with the Brewers also in the mix. The pitching matchup for the series opener will feature Reds' Brady Singer (7-4, 4.34) against Cardinals' Andre Pallante (4-3, 4.83). St. Louis is the favorite with a -133 line. The game is set to start at 7:15 PM EST. Stay tuned for more insights on this matchup and consider our top picks to optimize your betting strategy.

Betting Odds

• Moneyline: Reds +116 | Cardinals -133
• Spread: Reds +1.5 (-180) | Cardinals -1.5 (+155)
• Total: Over/Under 9 (-110)
• Based on the moneyline, the implied probability that St. Louis will win straight-up is 57%.

Cincinnati vs St. Louis Stats

Cincinnati Reds

The Cincinnati Reds have a history of starting well but fading out of contention late in the season. This offseason, they brought in two-time World Series champion manager Terry Francona to change the team culture. After a slow start, the Reds are now heating up as they head towards the All-Star Break, winning four straight games before being trounced by the Twins. The team will face the St. Louis Cardinals in a three-game series, with Brady Singer starting on the hill. Singer has a 7-4 record this season with a 4.34 ERA and has won three of his last five starts. The Reds are dealing with key injuries to several players. With a power ranking of 7, the Reds are currently ranked 8th in offense, 14th in defense, and have a record of 39-36 this season.

St. Louis Cardinals Analysis

The St. Louis Cardinals are making a strong push in the NL Central Division this season after a disappointing 2024 campaign. They recently swept the White Sox in a doubleheader, with standout performances from Willson Contreras and Nolan Arenado. The Cardinals will look to overtake the Reds in the division standings in their upcoming series. Starting pitcher Andre Pallante will take the mound in the opener, with a record of 4-3 and an ERA of 4.83. The Cardinals are dealing with key injuries but have a strong offense, ranking 10th in the league. They currently have a 38-35 record and are ranked 21st overall in power rankings. The team is focused on continuing their winning streak and staying competitive in the division race.

Cardinals Look to Capitalize on Home Field Advantage Against Reds

The two teams have split their four games this season, with the Cardinals holding a +4 run differential advantage due to winning two blowouts. Furthermore, the Cardinals have demonstrated their dominance at home this season with a record of 22-14, while the Reds have a .500 record on the road. Singer, who is 0-1 against the Cardinals, performed well in a previous home game but has struggled on the road this season with an ERA over 5.00. Pallante, also 0-1 against the Reds, has a 2-2 home record, showcasing more consistency in that environment. A Cardinals victory on Friday will help close the gap in the NL Central standings. It is advisable to consider taking the Cardinals with the money line in this matchup.

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