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  1. Home
  2. MLB Picks
  3. San Diego Padres vs Toronto Blue Jays
Tue 7:07 PM ET
San Diego Padres logo
San Diego
Padres0
D. Cease RHP
versus
Toronto Blue Jays logo
Toronto
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C. Bassitt RHP
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San Diego Padres vs Toronto Blue Jays Betting Picks & Predictions

Game time: May 20, 2025 at 7:07 PM ET

Venue: Rogers Centre — Toronto, Ontario

Article updated May 20, 6:16 PM EDT

Published by SportsJaw Editorial Team

The San Diego Padres will be facing the Toronto Blue Jays in an interleague series at Rogers Centre on Tuesday night. The Padres, with a record of 91-71, will be looking to

Game outlook

The San Diego Padres will be facing the Toronto Blue Jays in an interleague series at Rogers Centre on Tuesday night. The Padres, with a record of 91-71, will be looking to take first place in the NL West. Dylan Cease, with a 4.60 ERA, will be starting for San Diego, while Chris Bassitt, with a 3.16 ERA, will be on the mound for Toronto. San Diego has a favorable record of 6-4 in their last 10 games against Toronto. The Padres are the betting favorites with an opening line of -121 that has not moved. Stay tuned to see which team comes out on top in this matchup.

Betting Odds

Moneyline: Padres -121 | Blue Jays +109

Spread: Padres -1.5 (+132) | Blue Jays +1.5 (-155)

Total: Over/Under 8 (-110)

Based on the moneyline, the implied probability that San Diego will win straight-up is 55%.

San Diego Padres

The San Diego Padres recently had their two series win streak snapped by the Seattle Mariners, getting swept in three games over the weekend. Despite this setback, the Padres are currently second in the NL West standings, one game behind Los Angeles. They will aim to take the series lead and move up in the standings with a win on Tuesday. San Diego's offense is averaging 4.50 runs per game, ranking them 13th in the league, with a .261 batting average that is third overall. Their .328 on base percentage places them ninth in the league, while their .396 slugging percentage is 13th. Manny Machado leads the team with a .317 batting average, while Fernando Tatis Jr. leads in home runs (12) and RBI (27). Defensively, the Padres are giving up an average of 3.58 runs per game, ranking sixth in the league. Opponents have a .218 batting average against San Diego, placing the Padres third in the league. Their 3.39 ERA is eighth, while their 1.17 WHIP is sixth. In their last game, Cease pitched 6.2 innings, allowing two runs on five hits in a 6-4 win over the Angels. He holds a 1-0 record with a 0.69 ERA in two games against Toronto. Currently, with a power ranking of 16, the San Diego Padres are ranked 13th in offense (4.50 runs per game), fifth in defense (allowing 3.52 runs per game), and have a season record of 91-71.

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MLB · San Diego Padres at Toronto Blue Jays

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Toronto Blue Jays Analysis

The Toronto Blue Jays suffered a loss to the Detroit Tigers after a previous win, and will look to bounce back in their upcoming game. Currently, the team is ranked 24th in offense, averaging 3.93 runs per game, while also ranking 22nd in defense, giving up 4.50 runs per game. Bo Bichette leads in batting average and RBI, with Daulton Varsho leading in home runs. Boston Bassitt, with a 4.91 ERA, has a 1-4 record against San Diego. Toronto has an overall power ranking of 17 and San Diego has won two out of their last three matchups against Toronto.

San Diego Padres Favored Over Toronto Blue Jays in Upcoming Matchup

The San Diego Padres have demonstrated their road game prowess by winning seven of their last nine matches, while the Toronto Blue Jays have struggled with six losses in their last eight road games. San Diego holds an advantage in this upcoming matchup due to their success against right-handed pitchers and the recent shaky performance of Bassitt on the mound, surrendering nine runs in his last three starts. Conversely, Toronto's offensive capabilities are hindered by their inconsistent hitting compared to the Padres, and Cease's reliable pitching record, allowing only five runs in his last three starts. With Cease's past success against the Blue Jays, it is expected that he will effectively contain their offense. Therefore, it is recommended to place a wager on San Diego to win on the money line.

SportsJawGame Predictions
Predicted score

Unavailable for this preview

Projected winnerUnavailableConfidencelow
Pick on the Spread

Published pick: Unavailable

Pick on the Total

Published pick: Unavailable

#SanDiegoPadres#TorontoBlueJays

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Written by

SportsJaw Editorial Team

SportsJaw published this archived preview from its original game-day article. Its prediction and quoted lines are preserved as written.

About our editorial process

SportsJaw Padres vs Blue Jays archived game preview contains historical odds and availability that may no longer be current. View history of past Padres vs Blue Jays matchups or learn how our predictions work.

Current matchup data

Lines, trends and availability

Line movement since open

  • Moneyline · San Diego Padres-121 → -108Moved
  • Moneyline · Toronto Blue Jays+109 → -105Moved
  • Spread · San Diego Padres-1.5 (+135) → -1.5 (+153)Moved
  • Spread · Toronto Blue Jays+1.5 (-155) → +1.5 (-174)Moved
  • Total · Over8 (-110) → 7.5 (-110)Moved
  • Total · Under8 (-110) → 7.5 (-110)Moved

ATS and O/U trends

San Diego Padres
91-71 matchup record · 5-5-0 ATS · 5-5-0 O/U
Last 10 completed games on file
Toronto Blue Jays
79-83 matchup record · 7-3-0 ATS · 6-3-1 O/U
Last 10 completed games on file

Injuries and availability

From the published research (2025-05-20T22:16:03.013Z). Availability may have changed; review the cited sources.

No verified injury or availability note was included in the published matchup research.

Recent head-to-head

No completed head-to-head result is available in the current history window.

Final result

Matchup pick recap

Toronto Blue Jays defeated San Diego Padres 3-0

Toronto Blue Jays defeated San Diego Padres 3-0 on May 20, 2025, a 3-run decision in the series. Toronto Blue Jays' strongest period was the 5th inning, when it outscored its opponent 2-0. Against SportsJaw's recorded San Diego Padres -1.5 (+153) spread, Toronto Blue Jays covered, while the 3 combined runs finished under the recorded total of 7.5.

SportsJaw editorial picks

  • Projected winnerNo published selectionUnavailable

Tipster picks

  • JohnTharpTotal · Under 8 (-110)Win
  • Steve512Moneyline · San Diego Padres -120Loss