San Diego Padres vs
Pittsburgh PiratesPredictions & Preview

Padres vs. Pirates: San Diego Set as Betting Favorite for National League Matchup at PNC Park

The San Diego Padres will be facing off against the Pittsburgh Pirates at PNC Park on Friday night, with first pitch scheduled for 6:40 p.m. ET. The Padres have historically performed well against the Pirates, winning seven out of their last ten meetings. Dylan Cease will be the starting pitcher for the Padres, while Mitch Keller will be starting for the Pirates. San Diego is the betting favorite, opening at -144. Stay tuned for our Padres vs. Pirates prediction.

Betting Odds

• Moneyline: Padres -144 | Pirates +131
• Spread: Padres -1.5 (+118) | Pirates +1.5 (-142)
• Total: Over/Under 8 (-110)
• Based on the moneyline, the implied probability that San Diego will win straight-up is 59%.

San Diego vs Pittsburgh Stats

San Diego Padres

The San Diego Padres recently swept a two-game series against San Francisco and have a record of 19-11 SU, 18-12 RL, and 12-17-1 O/U. The team will start right-hander Dylan Cease against Pittsburgh, who has a 1-2 record with a 5.76 ERA in six starts. San Diego had a successful 2024 season, nearly upsetting the eventual champion Los Angeles. Despite injuries to key players, the Padres remain a threat for a Wild Card spot in the 2025 season. There are no recent injuries to report for the upcoming game against the Pirates. San Diego is ranked 22 in offense, second in defense, and holds a power ranking of 10 with a 19-11 record this season.

Pittsburgh Pirates Analysis

The Pittsburgh Pirates, with a record of 12-20, recently lost two out of three games to Chicago. The team is 4-6 in their last ten games and will have Mitch Keller starting against San Diego. Keller has a 1-2 record with a 3.97 ERA in six starts this season. Paul Skenes is expected to be a highlight of the 2025 season for the Pirates. Other young players will need to step up for the team to improve in the standings. The Pirates have no new injuries for their upcoming game against the Padres. The team is ranked 19th overall and 25th for offense, scoring an average of 3.40 runs per game and giving up an average of 4.53 runs per game. San Diego lost all three games in their last series against Pittsburgh.

Expert Analysis and Predictions for Padres vs. Pirates National League Matchup: Who Will Emerge Victorious?

Discover who will emerge victorious in the upcoming National League matchup between the Padres and Pirates by exploring our in-depth analysis and prediction. Stay informed on key players, recent performances, and strategies that may impact the outcome of the game. Follow along as we break down the strengths and weaknesses of each team to provide you with valuable insights. Make sure to check back for updates and expert commentary leading up to the game. Don't miss out on this exciting face-off between two talented teams as they battle for supremacy in the National League.

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