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Cleveland Guardians vs
Cincinnati RedsPredictions & Preview
Guardians vs Reds Preview: Cleveland Favored as Ohio Rivals Clash in MLB's Rivalry Weekend
In this preview of the Guardians at Reds matchup, both teams are looking to secure a win as they face off in Cincinnati during MLB's rivalry weekend. The Guardians are currently chasing the Tigers in the AL Central Division, while the Reds have fallen to fourth place in the NL Central. The series opener will feature Slade Cecconi pitching for the Guardians and Chase Petty on the mound for the Reds. The game is set to start at 6:40 PM EST. Cleveland is favored to win with Luis Ortiz as the starting pitcher, and the betting line has remained stable. Be sure to read on for more insights and betting tips for this exciting game.
Betting Odds
- Moneyline: Guardians -123 | Reds +108
- Spread: Guardians -1.5 (+125) | Reds +1.5 (-145)
- Total: Over/Under 10 (-110)
- Based on the moneyline, the implied probability that Cleveland will win straight-up is 55%.
Cleveland vs Cincinnati Stats

Cleveland Guardians
The Cleveland Guardians are aiming for another playoff appearance in 2025 and their third AL Central Division title in four seasons. Despite being three games behind the Tigers in the division, the Guardians are optimistic after recent wins against the Brewers. However, they suffered a 9-5 loss in the series finale due to their bullpen giving up seven runs in the final four innings. Jose Ramirez was a standout player with a homer and three RBIs in the game. The Guardians will rely on righty Slade Cecconi in their upcoming game against the Reds, his first start of the season after returning from an oblique injury. Cecconi, acquired from the Diamondbacks, had a record of 2-7 last season with a 6.66 ERA. The team will be prepared to utilize their bullpen as needed. Despite key injuries to players like Mica Pries, Lane Thomas, and Erik Sabrowski, the Guardians have a 25-18 record and are ranked 20 in both offense and defense in the league.
Cincinnati Reds Analysis
The Cincinnati Reds are looking to gain ground in the NL Central Division standings as they face off against the Cleveland Guardians this weekend. Despite recent losses, the Reds secured a much-needed win on Thursday with standout performances from Nick Martinez and key hitters. As they prepare for the series, the Reds will rely on righty Chase Petty, who has struggled in his first two starts of the season. The team is also dealing with key injuries to Noelvi Marte and Rhett Lowder. With a power ranking of 18, the Reds rank #13 in offense and #14 in defense, holding a 21-24 overall record. The Guardians are coming off a 1-2 record in their last three matchups against Cincinnati.
Ohio Rivals Set to Face Off in High-Scoring Matchup, Guardians Favored with Ceccone Making First Start
This upcoming game between the Ohio rivals presents the potential for high-scoring excitement. It is notable that Ceccone will be making his first start of the year, while Petty has struggled to pitch more than four innings in his first two starts and has issued eight walks in just 5.1 innings. The strength of the Guardians' bullpen is likely to support Ceccone effectively, providing them with a competitive edge. Petty's susceptibility to giving up home runs may pose a challenge at The Great American Ballpark, offering the Guardians multiple opportunities for power hitting. Given Petty's recent performance, it is essential for him to demonstrate his capability as a reliable starter. Therefore, considering these factors, the advisable choice would be to consider the Guardians with the money line for this upcoming game.
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