San Francisco Giants vs
Minnesota TwinsPredictions & Preview

MLB Betting Action: Giants vs Twins Interleague Showdown Set for Saturday, May 10, 2025 at Target Field

On Saturday, May 10, 2025, the MLB betting action features a full 15-game card, including an interleague showdown between the San Francisco Giants and the Minnesota Twins at Target Field in Minneapolis, MN. The Twins are slight -115 moneyline favorites for Saturday's clash, with the total set at 7.5 runs. Starting pitchers Logan Webb (Giants) and Joe Ryan (Twins) will take the mound. Minnesota opened as -113 favorites, and the line has remained steady. The game is scheduled to begin at 7:15 PM ET.

Betting Odds

• Moneyline: Giants +103 | Twins -113
• Spread: Giants -1.5 (+162) | Twins +1.5 (-200)
• Total: Over/Under 7 (-110)
• Based on the moneyline, the implied probability that Minnesota will win straight-up is 53%.

San Francisco vs Minnesota Stats

San Francisco Giants

The San Francisco Giants are currently third in the NL West, one game behind the leading Los Angeles Dodgers. They have won consecutive series against the Rockies and Cubs, showcasing strong offensive and defensive performance throughout the season. The team has been scoring an average of 4.82 runs per game and yielding 3.79 runs in return, ranking 9th and 8th in the MLB, respectively. Their bullpen has also been performing well, with a 3.07 ERA and 1.16 WHIP over the last 10 days. Pitcher Logan Webb has been solid on the mound, boasting a 2.61 ERA with a 4-2 record this season. The Giants are set to face the Minnesota Twins, a team Webb has never met before, but has a 12-15 record with a 3.82 ERA in interleague starts. Overall, with a power ranking of 13, the Giants have shown a strong performance both offensively and defensively, with a 24-14 record this season.

Minnesota Twins Analysis

The Minnesota Twins are currently fourth in the AL Central, seven games behind the Detroit Tigers. They are seeking their sixth straight victory after winning consecutive series against Boston and Baltimore. The Twins rank 20th in runs scored and 6th in runs allowed in the majors. Their bullpen has a 3.52 ERA over the last 10 days. Joe Ryan is expected to start Saturday with a 2-2 record and a 2.93 ERA this season. He has been strong in his last two starts. The Twins will face San Francisco, against whom Ryan has a 2-1 record with a 3.31 ERA in his career. The Giants are 9-for-33 against Ryan. Minnesota has a power ranking of 7 and is currently 20th in offense, scoring an average of 3.97 runs per game. San Francisco went 1-2 in their last three matchups against the Twins.

Twins Struggle Against Righties as Giants Shine: Prediction for Close Matchup

In the past 10 days, the Twins have faced challenges when playing against right-handed pitchers, posting a .655 OPS and 88 wRC+. In comparison, the Giants have excelled with a .761 OPS and 114 wRC+ in matchups against righties during the same timeframe. Given this information, my prediction is that the Giants will come out on top in what is likely to be a closely contested game. Both Logan Webb and Joe Ryan have demonstrated impressive performances this season, despite a few inconsistent starts. I anticipate a strong pitching performance from both players in this upcoming matchup. Additionally, the Giants currently showcase a more potent offensive lineup, which gives them a competitive advantage in this game.

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