San Diego Padres vs
Oakland AthleticsPredictions & Preview

San Diego Padres favored on the road against the Oakland Athletics in a crucial matchup at Sutter Health Park

On April 8, 2025, the San Diego Padres will face off against the Athletics in the second game of a three-game series at Sutter Health Park in Sacramento, CA. The Padres are the -135 road favorites with a total of 8.5 runs for the game. Dylan Cease will be the starting pitcher for the Padres, while Jeffrey Springs will take the mound for the Athletics. San Diego opened as -140 favorites, but the current line has them at -145. Stay tuned for the latest updates and analysis on this matchup in our Padres vs. Athletics prediction.

Betting Odds

• Moneyline: Padres -145 | Athletics +125
• Spread: Padres -1.5 (+115) | Athletics +1.5 (-135)
• Total: Over/Under 8.5 (-110)
• Based on the moneyline, the implied probability that San Diego will win straight-up is 59%.

San Diego vs Oakland Stats

San Diego Padres

The San Diego Padres started the season strong with a seven-game winning streak, including sweeping the Atlanta Braves and Cleveland Guardians at home. After dropping consecutive games in Chicago, they bounced back with an 8-7 win over the Cubs. Key performances included a two-run homer by Jackson Merrill and a 4-for-5 game from Luis Arraez. Closer Robert Suarez earned his fourth save of the season and has yet to allow a hit in 2025. Dylan Cease is set to pitch against the Athletics, boasting a 1-0 record with a 3.38 ERA and 1.03 WHIP in two starts this season. In terms of power rankings, San Diego is currently ranked 8 with an offense ranked 12th (scoring an average of 4.22 runs per game), leading in defense (allowing 2.33 runs per game), and holding an 8-2 record for the season.

Oakland Athletics Analysis

The Athletics suffered a heavy 12-5 defeat at Coors Field in Denver after winning the first two contests against the Colorado Rockies. Despite mustering nine hits and hitting two home runs, including a two-run dinger by Tyler Soderstrom and a solo homer by Lawrence Butler, the Athletics fell short. Joey Estes gave up six earned runs in just three innings of work. Jeffrey Springs is expected to pitch Tuesday with a 1-1 record, a 4.00 ERA, and a 1.44 WHIP. The Padres have a 0-3 record against Oakland in their last three matchups and only five players have seen Springs before, with limited success. The Athletics have a power ranking of 30, ranking #14 for offense, #26 for defense, and hold a 4-6 overall record.

Dylan Cease and Padres Bullpen Set to Play Key Roles in Outcome of Game Against Athletics

I anticipate that Dylan Cease, along with the Padres bullpen, will have a significant impact on the outcome of the game. Cease has performed admirably, while the Padres relievers have excelled with a 1.66 ERA and 0.95 WHIP in their first 43.1 innings in the 2025 season. Conversely, Jeffrey Springs struggled during his last outing, allowing the Cubs to capitalize on five hits and four walks. The Padres have demonstrated their proficiency against left-handed pitchers with a solid 105 wRC+ in 2025, suggesting they may have success against Springs early in the game. The Athletics may face challenges if they are forced to rely on their bullpen prematurely, as they have struggled with a 6.39 ERA and 1.71 WHIP across 38 innings pitched.

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