Baltimore Orioles vs
Arizona DiamondbacksPredictions & Preview

2025 MLB Season Opens with Baltimore Orioles vs Arizona Diamondbacks at Chase Field, Diamondbacks favored at -115 Moneyline

The 2025 Major League Baseball season will kick off with a game between the Baltimore Orioles and the Arizona Diamondbacks at Chase Field in Phoenix, AZ on Tuesday, April 8. The Diamondbacks are slight -115 moneyline favorites for the game, with a total of 9.0 runs. Starting pitchers will be Charlie Morton for the Orioles and Merrill Kelly for the Diamondbacks. Arizona is currently listed as -116 favorites. The game is set to begin at 9:40 PM ET.

Betting Odds

• Moneyline: Orioles +103 | Diamondbacks -116
• Spread: Orioles +1.5 (-190) | Diamondbacks -1.5 (+165)
• Total: Over/Under 9 (-110)
• Based on the moneyline, the implied probability that Arizona will win straight-up is 54%.

Baltimore vs Arizona Stats

Baltimore Orioles

The Baltimore Orioles have struggled in the early stages of the season, dropping six of their first 10 games. Despite scoring 47 runs and hitting 11 home runs, the team has had difficulty stringing together consistent wins. On the pitching side, the Orioles have posted a 4.71 ERA and a 1.41 WHIP. Charlie Morton, who has had a rough start to the season with a 0-2 record and a 9.72 ERA, will be starting the upcoming game against the Arizona Diamondbacks. The Orioles are currently ranked 12th in power rankings, with a strong offense but a defense that has allowed an average of 4.78 runs per game. They have a 4-6 record so far this season.

Arizona Diamondbacks Analysis

The Arizona Diamondbacks recently completed a six-game road trip with a 3-3 record, winning two out of three games against the New York Yankees but losing all three games against the Washington Nationals. In their first 10 games of the season, the Diamondbacks have shown strong offensive performance with 58 runs scored and a .261/.350/.450 slash line with 12 home runs in 333 at-bats. However, their pitching staff has struggled with a 5.07 ERA, 1.24 WHIP, and a .231 batting average against. Tuesday's starting pitcher, Merrill Kelly, has had mixed performances this season, posting a 1-1 record with a 10.00 ERA and 2.11 WHIP. In his last outing, Kelly struggled against the Yankees, giving up nine earned runs in just 3.2 innings. The Diamondbacks have a power ranking of 6 and are ranked 4th in offense, scoring an average of 6.00 runs per game, but are ranked 23rd in defense, giving up an average of 5.11 runs per game. In their last three matchups against Baltimore, Arizona won one out of three games.

Arizona Diamondbacks Face Challenge of Missing 2B Ketel Marte, Look to Overcome Setback with Strong Hitting Lineup and Potential Pitching Improvements

Arizona Diamondbacks are currently facing the challenge of being without 2B Ketel Marte due to a hamstring injury. This absence poses a significant setback for the team, however, they still have a formidable lineup of hitters. Despite Merrill Kelly's recent performance on the road against the Yankees, he displayed a strong showing at home against the Cubs. This suggests the potential for an improved performance in the upcoming games. The Baltimore Orioles, on the other hand, face uncertainties regarding LF Colton Cowser. The limited exposure of Orioles players to Kelly in the past, with only four hits in 35 at-bats from five players, may work in favor of the Diamondbacks. In contrast, the current Diamondbacks lineup has displayed a strong track record against Charlie Morton, with a collective 24 hits in 101 at-bats. Notably, Geraldo Perdomo has particularly excelled, with a 5-for-9 record against Morton, including two doubles.

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