Cleveland Guardians vs
Los Angeles AngelsPredictions & Preview

MLB Betting Preview: Cleveland Guardians Favored to Win Against Los Angeles Angels

On April 4, 2025, the MLB betting action continues with a 14-game card, including a matchup between the Cleveland Guardians and Los Angeles Angels at Angel Stadium in Anaheim, CA. The Guardians are favored to win with a -120 moneyline and a total of 7.5 runs. Gavin Williams will be starting for Cleveland, while Jose Soriano will take the mound for the Angels. The betting line has not shifted since opening at -117 for Cleveland. For more insights and predictions on this game and others on Friday's slate, be sure to visit our website.

Betting Odds

• Moneyline: Guardians -117 | Angels +103
• Spread: Guardians -1.5 (+137) | Angels +1.5 (-163)
• Total: Over/Under 8 (-110)
• Based on the moneyline, the implied probability that Cleveland will win straight-up is 54%.

Cleveland vs Los Angeles Stats

Cleveland Guardians

The Cleveland Guardians started the season with a mixed performance on the road, winning two out of three games against the Kansas City Royals but being swept by the San Diego Padres. Their offense has struggled, slashing .227/.295/.392 with limited extra-base hits. On the pitching side, they have a 4.41 ERA and a .276 batting average against. Gavin Williams will be starting against the Angels on Friday night after a solid season debut. The Guardians are currently ranked 20th in offense and defense, with a power ranking of 17, and have a 2-4 record so far this season.

Los Angeles Angels Analysis

The Los Angeles Angels started the season with two successful three-game road series against the Chicago White Sox and St. Louis Cardinals, scoring 24 runs while allowing 33 in return. Despite a tough loss to the Cardinals, the Angels are hitting .198/.267/.310 with six doubles, two triples, and four home runs in 197 at-bats. Their pitching staff has a 4.58 ERA, 1.38 WHIP, and .249 batting average against. Jose Soriano will be starting on Friday after a strong season debut last Saturday. Soriano has a promising track record and has performed well against the Guardians in the past. The Angels currently hold a power ranking of 28 and are ranked #18 for offense and #14 for defense, with an overall record of 4-2. Their upcoming matchup against the struggling Cleveland team could be in their favor based on recent performance trends.

Cleveland Guardians poised for victory against struggling Angels squad

In 2024, Jose Soriano faced the Guardians twice, performing well in one game and struggling in the other. Despite the Guardians having a 7-for-21 record with a home run against Soriano, the current trend shows Cleveland has been undefeated in five consecutive games against the Angels. It is anticipated that Cleveland will continue to dominate in their upcoming matchup. Only one player from the Angels team has prior experience facing Gavin Williams. The Angels lineup has displayed weak performance in the initial six games of the season, with a 60 wRC+ against right-handed pitchers. On the other hand, Cleveland has a 78 wRC+ against right-handed pitchers, indicating room for improvement. However, the offensive strengths of the Guardians appear to be more formidable in comparison to Los Angeles.

Sources: [ 2 ] [ 3 ]