Milwaukee Brewers vs
Chicago White SoxPredictions & Preview

White Sox Rookie Shane Smith Aims to Upset Brewers in Interleague Showdown

The 2025 Major League Baseball season continues with an interleague showdown between the Milwaukee Brewers and Chicago White Sox on Wednesday, April 30 at Rate Field in Chicago, IL. The Brewers are currently -185 moneyline favorites for the game, with a total of 8.0 runs. Tobias Myers will be the starting pitcher for the Brewers, while Shane Smith will be starting for the White Sox. The first pitch is set for 7:40 PM ET. For more information on this matchup and other MLB picks for Wednesday's card, read on.

Betting Odds

• Moneyline: Brewers -158 | White Sox +138
• Spread: Brewers -1.5 (+110) | White Sox +1.5 (-130)
• Total: Over/Under 7.5 (-110)
• Based on the moneyline, the implied probability that Milwaukee will win straight-up is 61%.

Milwaukee vs Chicago Stats

Milwaukee Brewers

The Milwaukee Brewers have had a shaky start to the season due to inconsistencies in their offense and a serious injury crisis on the pitching side. Three starters are currently missing from the lineup, with Tobias Myers recently returning from the IL. The Brewers managed to break a four-game losing streak by defeating the St. Louis Cardinals 7-1 last Sunday. In the past week, the team has shown improvement at the plate but has struggled with power hitting. Myers, who suffered an oblique injury in spring training, made his season debut last Thursday with a solid performance. Despite their current struggles, the Brewers are ranked 5th in offense and 20th in defense, with a record of 14-15 so far this season.

Chicago White Sox Analysis

The Chicago White Sox faced a tough 3-2 extra-inning loss to the Athletics, missing a chance to win a three-game series. They sit at the bottom of the American League, eight games behind the final wild-card spot. Despite scoring 10 runs the previous day, the White Sox have struggled, with their bullpen posting a 4.28 ERA in the last seven days. Rookie pitcher Shane Smith is set to start Wednesday, boasting a 2.30 ERA in five starts. The team currently holds a power ranking of 27, ranking #27 in offense and #16 in defense, with a record of 7-21. Milwaukee has lost their last three matchups against the White Sox.

White Sox rookie Shane Smith looks to lead team to upset over Brewers

Tobias Myers faced challenges with control during his season debut, likely due to recovery from an oblique injury. Given this, it is reasonable to speculate that he may require some additional time to fully regain his form. Consequently, the possibility of the White Sox causing an upset against the Brewers in this game should not be overlooked. To achieve this, the White Sox will be relying on the performance of rookie pitcher, Shane Smith, who has demonstrated impressive statistics thus far. Smith's exceptional off-speed run value and practically unhittable changeup are notable strengths. Both teams have shown strong performances against right-handed pitchers recently, with the White Sox showcasing a .709 OPS and 108 wRC+, and the Brewers recording a .723 OPS and 107 wRC+. Concerns regarding the White Sox bullpen should be acknowledged, though there may be value in considering Chicago's runline based on the Brewers' recent bullpen track record of 0-3 with a 3.48 ERA over the past nine games.

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