Tampa Bay Rays vs
San Diego PadresPredictions & Preview

San Diego Padres Look to Rebound Against Tampa Bay Rays After Rare Home Loss

On Saturday evening, the Tampa Bay Rays (12-14) are set to face off against the San Diego Padres (17-9) in a highly anticipated matchup. The Rays took game one of the series with a 1-0 victory. Ryan Pepiot will take the mound for the Rays, while Dylan Cease will start for the Padres. San Diego is the betting favorite with the current line set at -140. Stay tuned for our Rays vs Padres Prediction for more insights into this game.

Betting Odds

• Moneyline: Rays +124 | Padres -140
• Spread: Rays +1.5 (-185) | Padres -1.5 (+161)
• Total: Over/Under 7 (-110)
• Based on the moneyline, the implied probability that San Diego will win straight-up is 58%.

Tampa Bay vs San Diego Stats

Tampa Bay Rays

The Tampa Bay Rays are currently looking to find their rhythm in the 2025 season after a somewhat inconsistent start, sitting at 12-14. Pitcher Ryan Pepiot will take the mound, hoping to improve his 1-3 record and 4.82 ERA by minimizing free passes and commanding the game against a tough Padres lineup. Veteran hitters like Yandy Díaz and Brandon Lowe are stabilizing the lineup, while young talents like Curtis Mead and Junior Caminero are making an impact. The bullpen, led by closer Pete Fairbanks, remains a dependable unit. Tampa Bay's offense thrives on quality at-bats and aggressiveness on the basepaths. With a power ranking of 19, the Rays are ranked 16th in offense, 8th in defense, and will need to bring a sharper offensive effort against the Padres to secure a win.

San Diego Padres Analysis

The San Diego Padres are currently in a strong position with a 17-9 record and leading the NL West, despite coming off a rare home loss to the Rays. They will be looking to bounce back in Saturday's game. Dylan Cease, who has historically performed well at Petco Park, will be starting on the mound. The Padres' lineup, featuring players like Fernando Tatis Jr., Manny Machado, and Luis Arraez, remains potent and dangerous. Defensively, the Padres have been solid all season, with a strong bullpen led by closer Robert Suárez. Despite Friday's loss, the Padres' pitching staff kept the game tight. With a motivated offense and Cease's track record at Petco, the Padres aim to avoid dropping their second straight home game. Their power ranking is 3, ranking #21 in offense and #2 in defense. Tampa Bay has won 1 out of their last 3 matchups against the Padres.

San Diego Padres Primed for Rebound After Rare Home Loss

The San Diego Padres are in a favorable position to rebound following a rare home defeat on Friday evening. Despite their 1-0 loss in the series opener, the Padres have demonstrated strong performance at Petco Park throughout the season. The team possesses a talented lineup led by Fernando Tatis Jr., Manny Machado, and Luis Arraez, which should have no trouble generating offense against Ryan Pepiot, who has struggled with consistency this season, evidenced by his 4.82 ERA. Dylan Cease's impressive career numbers at Petco Park further bolster the Padres' advantage. The team's bullpen, ranked among the best in the National League, provides an additional edge in tight games. Anticipate the Padres to approach the upcoming game with urgency, aiming to seize control early and capitalize on scoring opportunities. Ultimately, the Padres are poised to bounce back convincingly and even the series with a dominant performance.

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