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  1. Home
  2. MLB Picks
  3. Milwaukee Brewers vs St. Louis Cardinals
Sat 2:15 PM ET
Milwaukee Brewers logo
Milwaukee
Brewers5
Q. Priester RHP
versus
St. Louis Cardinals logo
St. Louis
Cardinals6
S. Gray RHP
Final
Team123456789T
Milwaukee Brewers0000210025
St. Louis Cardinals0122000

Milwaukee Brewers vs St. Louis Cardinals Betting Picks & Predictions

Game time: April 26, 2025 at 2:15 PM ET

Venue: Busch Stadium — St. Louis, Missouri

Article updated Apr 25, 10:00 PM EDT

Published by SportsJaw Editorial Team

In this upcoming divisional series matchup between the Milwaukee Brewers and the St. Louis Cardinals, the Brewers will have Quinn Priester on the mound facing off against the

Game outlook

In this upcoming divisional series matchup between the Milwaukee Brewers and the St. Louis Cardinals, the Brewers will have Quinn Priester on the mound facing off against the Cardinals' ace, Sonny Gray. Last season, the Brewers had a winning record of 8-5 against the Cardinals. St. Louis is currently favored to win this game with a -150 opening line. Will the Brewers be able to secure a road win to start off the season series against the Cardinals? Stay tuned for the Brewers vs. Cardinals prediction.

Betting Odds

Moneyline: Brewers +136 | Cardinals -150

Spread: Brewers +1.5 (-156) | Cardinals -1.5 (+130)

Total: Over/Under 7.5 (-110)

Based on the moneyline, the implied probability that St. Louis will win straight-up is 60%.

Milwaukee Brewers

On Saturday, Quinn Priester will be starting for the Milwaukee Brewers. Priester has been performing well, with a 1.93 ERA and a 1-0 record in his last 14 innings. This will be his first meeting against the Cardinals. The Brewers have been struggling with injuries to their pitching staff, but continue to perform just above the .500 mark. Young star Jackson Chourio has been a standout player, hitting five home runs and 20 RBIs with a .743 OPS. Brice Turang and William Contreras have also been productive offensively. The team is currently averaging 5.08 runs per game, ranking them fourth in the league. Their pitching, however, has been mediocre with a 4.23 ERA. Milwaukee has a power ranking of 2, is ranked 5th in offense, 19th in defense, and has a 103-59 record this season.

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MLB · Milwaukee Brewers at St. Louis Cardinals

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21+. Gambling problem? Call 1-800-GAMBLER. Picks are opinions, not guarantees. Past results do not predict future outcomes.

St. Louis Cardinals Analysis

The St. Louis Cardinals will have Sonny Gray on the mound for their upcoming game. Gray has been solid, with a 3.41 ERA and a 0.86 WHIP, and a 3-0 record in 29 innings pitched. The Cardinals have struggled with pitching this season, dropping two straight series and yielding 15 runs in their last series. Nolan Arenado has cooled down recently, but Brendan Donovan has been performing well with a .345 batting average. Masyn Winn, on the other hand, has struggled with a .605 OPS. The Cardinals are averaging 4.80 runs per game and have a 4.38 ERA, ranking them 8th and 22nd in the league, respectively. They have a power ranking of 13 and are ranked 7th in offense. Milwaukee has won 2 out of their last 3 matchups against St. Louis.

Milwaukee Brewers Dominate St. Louis Cardinals as Pitching Duel Heats Up

During the previous season, the Milwaukee Brewers outperformed the St. Louis Cardinals, claiming victory in the series with an 8-5 advantage. The St. Louis Cardinals are currently facing difficulties, having lost four of their last five series and six of their last eight games. Meanwhile, pitcher Quinn Priester of the Brewers has exhibited strong performance, allowing two or fewer runs in all three of his appearances this season, notably pitching five scoreless innings against Detroit. On the other hand, Cardinals pitcher Sonny Gray has been consistent but has struggled with giving up five home runs in his five recent starts. Gray recorded a suboptimal 4.42 ERA and a winless 0-2 record against Milwaukee in the previous season.

SportsJawGame Predictions
Predicted score

Unavailable for this preview

Projected winnerUnavailableConfidencelow
Pick on the Spread

Published pick: Unavailable

Pick on the Total

Published pick: Unavailable

#MilwaukeeBrewers#StLouisCardinals

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Written by

SportsJaw Editorial Team

SportsJaw published this archived preview from its original game-day article. Its prediction and quoted lines are preserved as written.

About our editorial process

SportsJaw Brewers vs Cardinals archived game preview contains historical odds and availability that may no longer be current. View history of past Brewers vs Cardinals matchups or learn how our predictions work.

Current matchup data

Lines, trends and availability

Line movement since open

  • Moneyline · Milwaukee Brewers+136 → +126Moved
  • Moneyline · St. Louis Cardinals-150 → -146Moved
  • Spread · Milwaukee Brewers+1.5 (-156) → +1.5 (-164)Moved
  • Spread · St. Louis Cardinals-1.5 (+130) → -1.5 (+140)Moved
  • Total · Over7.5 (-110) → 7 (-110)Moved
  • Total · Under7.5 (-110) → 7 (-110)Moved

ATS and O/U trends

Milwaukee Brewers
103-59 matchup record · 7-3-0 ATS · 3-6-1 O/U
Last 10 completed games on file
St. Louis Cardinals
77-85 matchup record · 4-6-0 ATS · 4-6-0 O/U
Last 10 completed games on file

Injuries and availability

From the published research (2025-04-26T02:00:57.411Z). Availability may have changed; review the cited sources.

On Saturday, Quinn Priester will be starting for the Milwaukee Brewers. Priester has been performing well, with a 1.93 ERA and a 1-0 record in his last 14 innings. This will be his first meeting against the Cardinals. The Brewers have been struggling with injuries to their pitching staff, but continue to perform just above the .500 mark. Young star Jackson Chourio has been a standout player, hitting five home runs and 20 RBIs with a .743 OPS. Brice Turang and William Contreras have also been productive offensively. The team is currently averaging 5.08 runs per game, ranking them fourth in the league. Their pitching, however, has been mediocre with a 4.23 ERA. Milwaukee has a power ranking of 2, is ranked 5th in offense, 19th in defense, and has a 103-59 record this season.

Recent head-to-head

  • 2025-04-25Milwaukee Brewers 2 · St. Louis Cardinals 3
Final result

Matchup pick recap

St. Louis Cardinals defeated Milwaukee Brewers 6-5

St. Louis Cardinals defeated Milwaukee Brewers 6-5 on April 26, 2025, a 1-run decision in the series. St. Louis Cardinals' strongest period was the 3rd inning, when it outscored its opponent 2-0. Against SportsJaw's recorded Milwaukee Brewers +1.5 (-164) spread, Milwaukee Brewers covered, while the 11 combined runs finished over the recorded total of 7.

SportsJaw editorial picks

  • Projected winnerNo published selectionUnavailable

Tipster picks

  • PeytoncTotal · Under 7.5 (-110)Loss
  • GustavosintoMoneyline · Milwaukee Brewers +135Loss
  • CovergirlTotal · Over 7.5 (-110)Win
  • NutinbutlocksTotal · Over 7.5 (-110)Win
  • EXCELent Sports PicksRunline · Milwaukee Brewers +1.5 (-160)Win