Pittsburgh Pirates vs
Los Angeles DodgersPredictions & Preview

Los Angeles Dodgers Favored Against Pittsburgh Pirates in National League Matchup at Dodger Stadium

The 2025 MLB season continues on Friday, April 25, with the Pittsburgh Pirates facing off against the Los Angeles Dodgers in a National League matchup at Dodger Stadium. The Dodgers are -180 moneyline favorites for the game, with Pittsburgh meeting Los Angeles for the first time this season. Last season, the Dodgers had a 4-2 record against the Pirates, including a three-game home sweep. Paul Skenes will start on the mound for the Pirates, with Yoshinobu Yamamoto taking the mound for the Dodgers. The game is set for a 10:10 PM ET first pitch, with Los Angeles currently favored at -202. For more insights and MLB picks for Friday's games, continue reading our Pittsburgh vs. Los Angeles prediction.

Betting Odds

• Moneyline: Pirates +171 | Dodgers -202
• Spread: Pirates +1.5 (-135) | Dodgers -1.5 (+115)
• Total: Over/Under 7 (-110)
• Based on the moneyline, the implied probability that Los Angeles will win straight-up is 67%.

Pittsburgh vs Los Angeles Stats

Pittsburgh Pirates

Thursday's games were not included in the analysis. The Pittsburgh Pirates, with a record of 10-15, visited the Los Angeles Angels aiming to complete a three-game sweep. The Pirates won the first two games, 9-3 and 3-0. However, the team ranks 24th in the MLB in runs scored per game (3.60) and 27th in OPS (.639), indicating a need for improvement in their offense. They have also struggled with home runs, ranking near the bottom in the league with only 18. On the pitching side, they have a solid 3.84 ERA, 1.17 WHIP, and .226 batting average against. Paul Skenes is set to pitch in the upcoming game at Dodger Stadium. The 22-year-old right-hander has performed well this season with a 2.87 ERA, 0.80 WHIP, and a 30/4 K/BB ratio. Despite his recent success, he has had mixed results against the Dodgers in the past. Overall, with a power ranking of 23, the Pirates are ranked 24th in offense, 14th in defense, and hold a season record of 10-16.

Los Angeles Dodgers Analysis

The Los Angeles Dodgers recently suffered a sweep at the hands of the Chicago Cubs, losing to them in two close games at Wrigley Field. This setback follows a stretch of inconsistency, with the Dodgers posting an 8-9 record over their last 17 games. Despite ranking ninth in the majors for runs scored per game and sixth in OPS, the team has struggled in the past few outings. Their pitching staff has maintained a decent performance, with Yoshinobu Yamamoto expected to start the upcoming game with impressive stats. The Dodgers currently have a power ranking of 15, ranking ninth in offense and 15th in defense. Facing the Pittsburgh Pirates, who have recently had success against them, the Dodgers will look to bounce back from their recent losses.

Key Matchup between Pirates' Pitching and Dodgers' Offense to Determine Outcome

With Paul Skenes on the mound, the Pirates have a competitive chance against the Dodgers, but the strength of the Dodgers' offense is likely to be a deciding factor. Yoshinobu Yamamoto's recent performance, in which he allowed only one unearned run across three starts and 19 innings, presents a formidable challenge for the Pirates' lineup. Although the Dodgers bullpen has shown inconsistency with a 4.22 ERA and 4.06 FIP over the past 10 days, it is important to note that they faced the highly competitive Cubs during this period. Conversely, the Pirates bullpen has been more consistent with a 3.03 ERA and 2.55 FIP recently, yet their offense may struggle against Yamamoto, whom they have not faced before.

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