San Diego Padres vs
Detroit TigersPredictions & Preview

San Diego Padres to Face Detroit Tigers in Battle of Division Leaders at Comerica Park on April 22, 2025

The San Diego Padres and Detroit Tigers are set to face off at Comerica Park on April 22, 2025, with both teams leading their respective divisions and off to strong starts this season. Nick Pivetta will take the mound for the Padres, boasting an impressive ERA of 1.57, while Jack Flaherty will start for the Tigers with an ERA of 2.53. Detroit opens as the betting favorite, with the current line at -112. Stay tuned for the outcome of Monday night's game.

Betting Odds

• Moneyline: Padres -102 | Tigers -112
• Spread: Padres -1.5 (+160) | Tigers +1.5 (-194)
• Total: Over/Under 7.5 (-110)
• Based on the moneyline, the implied probability that Detroit will win straight-up is 53%.

San Diego vs Detroit Stats

San Diego Padres

The San Diego Padres are currently leading the NL West with a record of 16-6. Their offense ranks first in batting average and fourth in OPS, while also having good speed on the basepaths. The pitching staff has been elite, with the second-best ERA in MLB and the league's top strikeout rate. Fernando Tatis Jr. leads the team in multiple offensive categories, while Nick Pivetta and Michael King have excelled on the mound. Despite injuries to key players, the Padres recently avoided a sweep in Houston and continue to perform well overall, ranking 13th in offense and second in defense with a power ranking of 3.

Detroit Tigers Analysis

The Detroit Tigers currently have a record of 13-9, placing them first in the AL Central. Offensively, they rank 10th in runs per game (4.55), 11th in batting average (.246), and 15th in OPS (.708). They have similar power numbers to the Padres, ranking 16th in home runs but are near the bottom in stolen bases. On the mound, the Tigers have a strong third-best ERA (3.12) and fifth-best WHIP (1.14), but have a low strikeout rate and are average in quality starts and errors. Spencer Torkelson leads the team in home runs and OPS, while Kerry Carpenter is hitting .315. Pitcher Casey Mize has emerged as the staff ace with a 2.22 ERA and three wins. The Tigers recently won three of four games from the Royals but lost their last matchup in extra innings. They have been successful as home favorites, covering the run line in five of seven games in that role this season. The Tigers have a power ranking of 4 and are ranked 9th in offense, averaging 4.62 runs per game, and 3rd in defense, giving up an average of 3.43 runs per game. San Diego recently went 1-2 in their last three matchups against Detroit.

San Diego Padres Face Detroit Tigers for Quick Turnaround Matchup

The San Diego Padres faced the Detroit Tigers on Monday following their previous game in Houston for Sunday night baseball. The quick turnaround from one game to the next can often result in fatigue for players. The Tigers currently hold a strong record, with an impressive 8-2 record at home and ranking as the second-best home money team in the American League. Based on their performance so far this season, it seems likely that the Tigers will come out on top in this match-up.

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