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  1. Home
  2. MLB Picks
  3. Los Angeles Angels vs St. Louis Cardinals
Wed 1:15 PM ET
Los Angeles Angels logo
Los Angeles
Angels5
Y. Kikuchi LHP
versus
St. Louis Cardinals logo
St. Louis
Cardinals12
S. Gray RHP
Final
Team123456789T
Los Angeles Angels1000004005
St. Louis Cardinals000102

Los Angeles Angels vs St. Louis Cardinals Betting Picks & Predictions

Game time: April 2, 2025 at 1:15 PM ET

Venue: Busch Stadium — St. Louis, Missouri

Article updated Apr 1, 10:16 PM EDT

Published by SportsJaw Editorial Team

The Los Angeles Angels will complete their series against the St. Louis Cardinals at Busch Stadium on Wednesday, with the first pitch scheduled for 1:15 p.m. ET. Last season,

Game outlook

The Los Angeles Angels will complete their series against the St. Louis Cardinals at Busch Stadium on Wednesday, with the first pitch scheduled for 1:15 p.m. ET. Last season, the Cardinals won two out of three games against the Angels, but the Angels hold a 6-4 advantage in the last ten matchups between the two teams. The majority of those games went over the total. Yusei Kikuchi will be the starting pitcher for the Angels, with a 4.5 ERA, while Sonny Gray will be starting for the Cardinals with a 3.6 ERA. The Cardinals are favored to win with a opening line of -138. For more information on the Angels vs. Cardinals prediction, continue reading.

Betting Odds

Moneyline: Angels +122 | Cardinals -138

Spread: Angels +1.5 (-181) | Cardinals -1.5 (+148)

Total: Over/Under 8 (-110)

Based on the moneyline, the implied probability that St. Louis will win straight-up is 58%.

Los Angeles Angels

Los Angeles Angels won their game against the Cardinals in extra innings, with Mike Trout leading the team with two RBI. Yusei Kikuchi will start for the Angels in their next game. The team made significant roster changes in the offseason, adding key players like Jorge Soler and Kyle Hendricks. Despite a historic number of losses last season, the Angels are off to a promising start this season with a 62-100 record. However, their offense is ranked 29th in the league, with an average of 1.67 runs per game. Despite some concerns in their bullpen, the Angels have shown potential for improvement.

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MLB · Los Angeles Angels at St. Louis Cardinals

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St. Louis Cardinals Analysis

The St. Louis Cardinals have started the season strong with a record of 77-85, showcasing a powerful offense that has scored 23 runs in their first four games. Despite a loss to Los Angeles, the team will rely on right-hander Sonny Gray in their upcoming game. The Cardinals finished second in the NL Central last season but have made few changes in the offseason, leading some to question their competitiveness. While a youth movement is underway, the team's experienced pitching staff indicates they are not in a full rebuild mode. The Cardinals currently have a power ranking of 5 and rank highly in both offense and defense. As for injuries, the team has none reported.

An In-Depth Look at the Los Angeles Angels vs. St. Louis Cardinals MLB Matchup: Expert Predictions and Insights

Discover insights into the highly anticipated MLB matchup between the Los Angeles Angels and the St. Louis Cardinals. In this detailed analysis, we provide a thorough prediction of the potential outcome of the game, highlighting key factors and statistics that may influence the final result. Stay informed and gain valuable knowledge about this exciting showdown by diving into our comprehensive breakdown of the Angels vs. Cardinals matchup. Explore expert opinions and trends to make an informed decision on the likely winner of this exciting baseball game.

SportsJawGame Predictions
Predicted score

Unavailable for this preview

Projected winnerUnavailableConfidencelow
Pick on the Spread

Published pick: Unavailable

Pick on the Total

Published pick: Unavailable

#LosAngelesAngels#StLouisCardinals

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Written by

SportsJaw Editorial Team

SportsJaw published this archived preview from its original game-day article. Its prediction and quoted lines are preserved as written.

About our editorial process

SportsJaw Angels vs Cardinals archived game preview contains historical odds and availability that may no longer be current. View history of past Angels vs Cardinals matchups or learn how our predictions work.

Current matchup data

Lines, trends and availability

Line movement since open

  • Moneyline · Los Angeles Angels+122 → +125Moved
  • Moneyline · St. Louis Cardinals-138 → -143Moved
  • Spread · Los Angeles Angels+1.5 (-181) → +1.5 (-168)Moved
  • Spread · St. Louis Cardinals-1.5 (+148) → -1.5 (+148)Unchanged
  • Total · Over8 (-110) → 8.5 (-110)Moved
  • Total · Under8 (-110) → 8.5 (-110)Moved

ATS and O/U trends

Los Angeles Angels
62-100 matchup record · 3-7-0 ATS · 4-5-1 O/U
Last 10 completed games on file
St. Louis Cardinals
77-85 matchup record · 7-3-0 ATS · 7-3-0 O/U
Last 10 completed games on file

Injuries and availability

From the published research (2025-04-02T02:16:00.254Z). Availability may have changed; review the cited sources.

The St. Louis Cardinals have started the season strong with a record of 77-85, showcasing a powerful offense that has scored 23 runs in their first four games. Despite a loss to Los Angeles, the team will rely on right-hander Sonny Gray in their upcoming game. The Cardinals finished second in the NL Central last season but have made few changes in the offseason, leading some to question their competitiveness. While a youth movement is underway, the team's experienced pitching staff indicates they are not in a full rebuild mode. The Cardinals currently have a power ranking of 5 and rank highly in both offense and defense. As for injuries, the team has none reported.

Recent head-to-head

  • 2025-04-01Los Angeles Angels 9 · St. Louis Cardinals 7
  • 2025-03-31Los Angeles Angels 5 · St. Louis Cardinals 4
Final result

Matchup pick recap

St. Louis Cardinals defeated Los Angeles Angels 12-5

St. Louis Cardinals defeated Los Angeles Angels 12-5 on April 2, 2025, a 7-run decision in the series. St. Louis Cardinals' strongest period was the 8th inning, when it outscored its opponent 7-0. Against SportsJaw's recorded Los Angeles Angels +1.5 (-168) spread, St. Louis Cardinals covered, while the 17 combined runs finished over the recorded total of 8.5.

SportsJaw editorial picks

  • Projected winnerNo published selectionUnavailable

Tipster picks

  • DpxsportsMoneyline · St. Louis Cardinals -138Win
  • MiamimikeMoneyline · St. Louis Cardinals -138Win